Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   NPS18_RS09165 Genome accession   NZ_CP101984
Coordinates   1851703..1852656 (-) Length   317 a.a.
NCBI ID   WP_002263442.1    Uniprot ID   Q8DS56
Organism   Streptococcus mutans strain UA-159     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1846703..1857656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS09140 (NPS18_09140) proC 1847652..1848422 (+) 771 WP_002263447.1 pyrroline-5-carboxylate reductase -
  NPS18_RS09145 (NPS18_09145) - 1848507..1849169 (-) 663 WP_002263446.1 type II CAAX endopeptidase family protein -
  NPS18_RS09150 (NPS18_09150) - 1849222..1849662 (-) 441 WP_002263445.1 hypothetical protein -
  NPS18_RS09155 (NPS18_09155) - 1849631..1849876 (-) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  NPS18_RS09160 (NPS18_09160) - 1850445..1851644 (-) 1200 WP_002263443.1 acetate kinase -
  NPS18_RS09165 (NPS18_09165) comYH 1851703..1852656 (-) 954 WP_002263442.1 class I SAM-dependent methyltransferase Machinery gene
  NPS18_RS09170 (NPS18_09170) comYG 1852711..1853100 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  NPS18_RS09175 (NPS18_09175) comYF 1853078..1853512 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  NPS18_RS09180 (NPS18_09180) comYE 1853499..1853792 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  NPS18_RS09185 (NPS18_09185) comYD 1853764..1854168 (-) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  NPS18_RS09190 (NPS18_09190) comYC 1854155..1854469 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  NPS18_RS09195 (NPS18_09195) comYB 1854469..1855500 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  NPS18_RS09200 (NPS18_09200) comYA 1855436..1856377 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  NPS18_RS09205 (NPS18_09205) - 1856507..1856890 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36272.56 Da        Isoelectric Point: 5.2379

>NTDB_id=713529 NPS18_RS09165 WP_002263442.1 1851703..1852656(-) (comYH) [Streptococcus mutans strain UA-159]
MDFEKIEAAYNLLLDNCQRLETQLHTHLYDALIEQNACYLGAEGADDFIKENNKKLRQLNLSKEEWRRSFQFIFIKATQS
QQLQSNHQFTPDSIGFIILYLLEGLTNKSQLDIIEIGSGTGNLAETIVNNSSKSIDYMGIEVDDLLIDLSASIADVLDSS
VHFVQEDAVRPQILKESDIIISDLPVGFYPNDKIAQRYQVAAKLGHTYAHHLLMEQSLKYLKKEGLAIFLAPVDLLTSEQ
SPLLKKWLQNNVTILAVISLPEAIFKQKSNIKSIFVLKKQSQQSLESFVYPLTDLQDPEVLRRFMKNFKKWKEDNVF

Nucleotide


Download         Length: 954 bp        

>NTDB_id=713529 NPS18_RS09165 WP_002263442.1 1851703..1852656(-) (comYH) [Streptococcus mutans strain UA-159]
ATGGATTTTGAAAAAATAGAAGCTGCCTATAACTTACTGTTAGATAATTGTCAAAGGCTGGAAACTCAACTTCATACTCA
CCTTTATGATGCCTTAATTGAGCAAAATGCTTGCTATCTAGGTGCTGAAGGTGCTGATGATTTTATTAAAGAAAATAATA
AAAAACTGCGTCAGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTAGTTTTCAATTTATTTTTATTAAGGCTACTCAAAGT
CAGCAATTACAGTCAAATCACCAATTTACACCAGATAGTATTGGTTTTATTATTCTTTATTTATTGGAAGGTTTAACAAA
TAAGAGTCAGTTAGACATCATTGAAATTGGTTCTGGGACAGGAAATCTTGCAGAGACTATTGTGAATAACAGTTCAAAAA
GCATTGATTATATGGGGATTGAGGTTGACGATCTGTTAATTGATTTATCAGCAAGTATTGCCGATGTATTGGATTCTTCT
GTGCATTTTGTTCAAGAAGATGCAGTGCGGCCTCAGATTTTAAAAGAAAGTGATATCATTATCAGTGATCTGCCAGTTGG
CTTTTATCCCAATGATAAAATTGCTCAGCGTTATCAGGTTGCAGCCAAGTTAGGACATACTTATGCACATCATCTTTTGA
TGGAGCAATCGCTTAAGTATTTAAAAAAAGAGGGACTTGCTATTTTTTTAGCGCCAGTGGATCTTTTAACTAGTGAGCAG
AGTCCTTTGCTTAAAAAGTGGTTACAGAACAATGTAACTATTTTAGCCGTTATTTCTTTACCTGAGGCAATTTTTAAACA
GAAAAGTAATATAAAGTCAATCTTTGTCTTAAAGAAACAATCGCAACAAAGTTTGGAAAGTTTTGTCTATCCTTTGACAG
ATTTACAAGACCCCGAAGTTTTAAGACGATTTATGAAAAATTTTAAAAAGTGGAAGGAAGATAATGTCTTTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(77-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DS56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

100

100

1
  comYH Streptococcus mutans UA140

99.369

100

0.994