Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   M2925_RS08075 Genome accession   NZ_CP097004
Coordinates   1678751..1679026 (-) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain LS05-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1673751..1684026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2925_RS08040 (M2925_08040) - 1674306..1674779 (+) 474 WP_002357065.1 universal stress protein -
  M2925_RS08045 (M2925_08045) - 1674891..1676078 (-) 1188 WP_002357064.1 acetate kinase -
  M2925_RS08050 (M2925_08050) - 1676103..1677110 (-) 1008 WP_002357063.1 class I SAM-dependent methyltransferase -
  M2925_RS08055 (M2925_08055) comGG 1677239..1677592 (-) 354 WP_002362054.1 competence type IV pilus minor pilin ComGG -
  M2925_RS08060 (M2925_08060) comGF 1677592..1678026 (-) 435 WP_002357060.1 competence type IV pilus minor pilin ComGF -
  M2925_RS08065 (M2925_08065) - 1678016..1678342 (-) 327 WP_085454834.1 type II secretion system protein -
  M2925_RS08070 (M2925_08070) comGD 1678308..1678754 (-) 447 WP_002379576.1 competence type IV pilus minor pilin ComGD -
  M2925_RS08075 (M2925_08075) comGC/cglC 1678751..1679026 (-) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  M2925_RS08080 (M2925_08080) comGB 1679026..1680072 (-) 1047 WP_002356990.1 competence type IV pilus assembly protein ComGB -
  M2925_RS08085 (M2925_08085) comGA 1680029..1680997 (-) 969 WP_002374519.1 competence type IV pilus ATPase ComGA -
  M2925_RS08090 (M2925_08090) - 1681241..1682569 (-) 1329 WP_010816624.1 amino acid permease -
  M2925_RS08095 (M2925_08095) rlmN 1682860..1683933 (-) 1074 WP_219259363.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=686048 M2925_RS08075 WP_002356991.1 1678751..1679026(-) (comGC/cglC) [Enterococcus faecalis strain LS05-2]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=686048 M2925_RS08075 WP_002356991.1 1678751..1679026(-) (comGC/cglC) [Enterococcus faecalis strain LS05-2]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTCCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582
  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571
  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571
  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549
  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538
  comYC Streptococcus suis isolate S10

52.326

94.505

0.495
  comYC Streptococcus mutans UA159

57.692

85.714

0.495
  comYC Streptococcus mutans UA140

57.692

85.714

0.495
  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462
  comGC Staphylococcus aureus MW2

46.835

86.813

0.407
  comGC Staphylococcus aureus N315

46.835

86.813

0.407
  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396