Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SCSC_RS08270 Genome accession   NZ_AP014647
Coordinates   1685984..1686925 (-) Length   313 a.a.
NCBI ID   WP_006269992.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1680984..1691925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS08230 (SCSC_1694) - 1681041..1682240 (-) 1200 WP_006269979.1 acetate kinase -
  SCSC_RS08235 (SCSC_1695) comYH 1682287..1683240 (-) 954 WP_006269998.1 class I SAM-dependent methyltransferase Machinery gene
  SCSC_RS08240 (SCSC_1696) comGG 1683325..1683651 (-) 327 WP_003070783.1 competence type IV pilus minor pilin ComGG -
  SCSC_RS08245 (SCSC_1697) comGF/cglF 1683632..1684069 (-) 438 WP_006270001.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCSC_RS08250 (SCSC_1698) comGE/cglE 1684053..1684346 (-) 294 WP_006269989.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCSC_RS08255 (SCSC_1699) comYD 1684318..1684716 (-) 399 WP_006269995.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCSC_RS08260 (SCSC_1700) comYC 1684706..1685023 (-) 318 WP_006269985.1 competence type IV pilus major pilin ComGC Machinery gene
  SCSC_RS08265 (SCSC_1701) comYB 1685020..1686042 (-) 1023 WP_037565861.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCSC_RS08270 (SCSC_1702) comYA 1685984..1686925 (-) 942 WP_006269992.1 competence type IV pilus ATPase ComGA Machinery gene
  SCSC_RS08275 (SCSC_1703) - 1686995..1687360 (-) 366 WP_006269973.1 DUF1033 family protein -
  SCSC_RS08280 (SCSC_1704) glnA 1687548..1688894 (-) 1347 WP_006269977.1 type I glutamate--ammonia ligase -
  SCSC_RS08285 (SCSC_1705) - 1688933..1689292 (-) 360 WP_003070793.1 MerR family transcriptional regulator -
  SCSC_RS08290 (SCSC_1706) - 1689369..1689899 (-) 531 WP_006269975.1 aromatic acid exporter family protein -
  SCSC_RS08295 (SCSC_1707) - 1690039..1690323 (-) 285 WP_006269982.1 2'-5' RNA ligase family protein -
  SCSC_RS08300 (SCSC_1708) - 1690326..1690532 (-) 207 WP_006269988.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 36008.15 Da        Isoelectric Point: 6.1148

>NTDB_id=66593 SCSC_RS08270 WP_006269992.1 1685984..1686925(-) (comYA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTFMHQLAQERFADQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHITFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=66593 SCSC_RS08270 WP_006269992.1 1685984..1686925(-) (comYA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTCAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGCGATTATCAA
TATAGTGACAAGAAAACATCGCTACGGTTATCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTTTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATAAAACTTTCTCTTCGGCATCGACCGGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

82.903

99.042

0.821
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.019

99.361

0.537
  comGA Latilactobacillus sakei subsp. sakei 23K

42.657

91.374

0.39

Multiple sequence alignment