Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SCSC_RS08250 Genome accession   NZ_AP014647
Coordinates   1684053..1684346 (-) Length   97 a.a.
NCBI ID   WP_006269989.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1679053..1689346
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS08230 (SCSC_1694) - 1681041..1682240 (-) 1200 WP_006269979.1 acetate kinase -
  SCSC_RS08235 (SCSC_1695) comYH 1682287..1683240 (-) 954 WP_006269998.1 class I SAM-dependent methyltransferase Machinery gene
  SCSC_RS08240 (SCSC_1696) comGG 1683325..1683651 (-) 327 WP_003070783.1 competence type IV pilus minor pilin ComGG -
  SCSC_RS08245 (SCSC_1697) comGF/cglF 1683632..1684069 (-) 438 WP_006270001.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCSC_RS08250 (SCSC_1698) comGE/cglE 1684053..1684346 (-) 294 WP_006269989.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCSC_RS08255 (SCSC_1699) comYD 1684318..1684716 (-) 399 WP_006269995.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCSC_RS08260 (SCSC_1700) comYC 1684706..1685023 (-) 318 WP_006269985.1 competence type IV pilus major pilin ComGC Machinery gene
  SCSC_RS08265 (SCSC_1701) comYB 1685020..1686042 (-) 1023 WP_037565861.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCSC_RS08270 (SCSC_1702) comYA 1685984..1686925 (-) 942 WP_006269992.1 competence type IV pilus ATPase ComGA Machinery gene
  SCSC_RS08275 (SCSC_1703) - 1686995..1687360 (-) 366 WP_006269973.1 DUF1033 family protein -
  SCSC_RS08280 (SCSC_1704) glnA 1687548..1688894 (-) 1347 WP_006269977.1 type I glutamate--ammonia ligase -
  SCSC_RS08285 (SCSC_1705) - 1688933..1689292 (-) 360 WP_003070793.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10903.84 Da        Isoelectric Point: 9.8363

>NTDB_id=66589 SCSC_RS08250 WP_006269989.1 1684053..1684346(-) (comGE/cglE) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MENLRKQCVRGTILLEALLALAVFAFIVTLLLGQIHQSRQTENDLLKKEEVLRVANMALQTKQSHLTINGIEVRVEKSQQ
GIQIYHGKELIVGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=66589 SCSC_RS08250 WP_006269989.1 1684053..1684346(-) (comGE/cglE) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGGAAAATTTAAGAAAACAATGCGTTAGAGGAACGATTTTATTAGAAGCTTTATTGGCATTGGCTGTTTTTGCGTTTAT
TGTGACCTTGTTATTGGGGCAGATCCATCAGTCTCGACAGACAGAAAATGATTTACTGAAAAAAGAAGAAGTTCTAAGAG
TGGCTAATATGGCATTACAAACAAAGCAAAGCCATTTAACAATAAACGGTATTGAAGTTCGTGTTGAAAAAAGTCAACAA
GGCATCCAGATTTATCATGGGAAGGAGCTGATTGTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comYE Streptococcus mutans UA140

43.434

100

0.443
  comYE Streptococcus mutans UA159

43.434

100

0.443

Multiple sequence alignment