Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG324_RS11120 Genome accession   NZ_CP108512
Coordinates   2379862..2380503 (-) Length   213 a.a.
NCBI ID   WP_327427678.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2374862..2385503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG324_RS11085 (OG324_11070) - 2374971..2375474 (+) 504 WP_327427671.1 HNH endonuclease -
  OG324_RS11090 (OG324_11075) - 2375600..2376535 (-) 936 WP_327427672.1 SPFH domain-containing protein -
  OG324_RS11095 (OG324_11080) - 2376666..2377100 (-) 435 WP_327427673.1 NfeD family protein -
  OG324_RS11100 (OG324_11085) - 2377195..2377986 (-) 792 WP_327427674.1 ABC transporter ATP-binding protein -
  OG324_RS11105 (OG324_11090) - 2378108..2378896 (+) 789 WP_327427675.1 hypothetical protein -
  OG324_RS11110 (OG324_11095) - 2378954..2379193 (-) 240 WP_327427676.1 chaplin -
  OG324_RS11115 (OG324_11100) - 2379413..2379658 (-) 246 WP_327427677.1 chaplin -
  OG324_RS11120 (OG324_11105) vraR 2379862..2380503 (-) 642 WP_327427678.1 response regulator transcription factor Regulator
  OG324_RS11125 (OG324_11110) - 2380496..2381647 (-) 1152 WP_327427679.1 GAF domain-containing sensor histidine kinase -
  OG324_RS11130 (OG324_11115) - 2381835..2382530 (+) 696 WP_327427680.1 SDR family NAD(P)-dependent oxidoreductase -
  OG324_RS11135 (OG324_11120) - 2382527..2383648 (+) 1122 WP_327427681.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG324_RS11140 (OG324_11125) - 2383948..2384697 (+) 750 WP_327427682.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22897.22 Da        Isoelectric Point: 5.3758

>NTDB_id=661871 OG324_RS11120 WP_327427678.1 2379862..2380503(-) (vraR) [Streptomyces sp. NBC_01236]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGIARAEELKPDVVLMDVKMPGMDGIEALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGGSLTEREREVL
SLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=661871 OG324_RS11120 WP_327427678.1 2379862..2380503(-) (vraR) [Streptomyces sp. NBC_01236]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAAGTGGTCCGCCGGGGCCTGCGCACCTTCCTCGAAGTACA
GGACGACATCGAGGTCGTGGGAGAGGCGTCCGACGGCGCCGAAGGGATCGCCCGCGCCGAGGAGTTGAAACCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGTATCGAGGCGCTGCGCAAGCTCCGCGAACTCGCCAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCCGCCCTGCGCGCGGGCGCCGCCGGGTATGTGTACAA
GGACGTGGACCCCGACGCCCTCGCCGGCGCCATCCGCTCCGTGCACGCCGGACACATCCTGCTGCAGCCCGAGGTCGCGG
GCGCGCTGCTGTCCCAGGAGGAGGCCAACTCGGGCCAGGGGAGAGGCGGTTCACTCACCGAGCGGGAGCGCGAGGTGCTC
AGCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCGCGCACTCGTCCTCTCCGAGAAGACCGTCAAGACGCATGT
CTCGAACATCCTGATGAAACTCGACCTCGCGGACCGGACCCAGGCCGCGCTCTGGGCCGTACGGCATGGGGTGGCAGGCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399