Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ML603_RS00710 Genome accession   NZ_CP092887
Coordinates   115276..116217 (+) Length   313 a.a.
NCBI ID   WP_241067295.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 110276..121217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS00700 (ML603_00700) rpoC 110985..114626 (+) 3642 WP_111714766.1 DNA-directed RNA polymerase subunit beta' -
  ML603_RS00705 (ML603_00705) - 114830..115195 (+) 366 WP_003055257.1 DUF1033 family protein -
  ML603_RS00710 (ML603_00710) comYA 115276..116217 (+) 942 WP_241067295.1 competence type IV pilus ATPase ComGA Machinery gene
  ML603_RS00715 (ML603_00715) comYB 116153..117184 (+) 1032 WP_241067698.1 competence type IV pilus assembly protein ComGB Machinery gene
  ML603_RS00720 (ML603_00720) comYC 117186..117512 (+) 327 WP_192942720.1 competence type IV pilus major pilin ComGC Machinery gene
  ML603_RS00725 (ML603_00725) comGD 117487..117915 (+) 429 WP_256867278.1 competence type IV pilus minor pilin ComGD -
  ML603_RS00730 (ML603_00730) comGE 117872..118168 (+) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  ML603_RS00735 (ML603_00735) comGF 118149..118589 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  ML603_RS00740 (ML603_00740) comGG 118618..118941 (+) 324 WP_226955945.1 competence type IV pilus minor pilin ComGG -
  ML603_RS00745 (ML603_00745) comYH 119004..119957 (+) 954 WP_192942722.1 class I SAM-dependent methyltransferase Machinery gene
  ML603_RS00750 (ML603_00750) - 120016..121212 (+) 1197 WP_084916957.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35233.38 Da        Isoelectric Point: 7.1044

>NTDB_id=660901 ML603_RS00710 WP_241067295.1 115276..116217(+) (comYA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MVQALARSILKEAEQMQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGEDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVAHQIGGRGLYLFAGPVGSGKTTLMHQLIADYYKGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLATGHLSPEQARLEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=660901 ML603_RS00710 WP_241067295.1 115276..116217(+) (comYA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATGCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGAAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGGAATTATCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACGGTTGCGCATCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATAAGGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTCCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAACGGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.415

99.361

0.61
  comYA Streptococcus mutans UA159

61.415

99.361

0.61
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

99.042

0.61
  comYA Streptococcus gordonii str. Challis substr. CH1

61.093

99.361

0.607
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.129

99.361

0.597
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514