Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ML603_RS00715 Genome accession   NZ_CP092887
Coordinates   116153..117184 (+) Length   343 a.a.
NCBI ID   WP_241067698.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111153..122184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS00705 (ML603_00705) - 114830..115195 (+) 366 WP_003055257.1 DUF1033 family protein -
  ML603_RS00710 (ML603_00710) comYA 115276..116217 (+) 942 WP_241067295.1 competence type IV pilus ATPase ComGA Machinery gene
  ML603_RS00715 (ML603_00715) comYB 116153..117184 (+) 1032 WP_241067698.1 competence type IV pilus assembly protein ComGB Machinery gene
  ML603_RS00720 (ML603_00720) comYC 117186..117512 (+) 327 WP_192942720.1 competence type IV pilus major pilin ComGC Machinery gene
  ML603_RS00725 (ML603_00725) comGD 117487..117915 (+) 429 WP_256867278.1 competence type IV pilus minor pilin ComGD -
  ML603_RS00730 (ML603_00730) comGE 117872..118168 (+) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  ML603_RS00735 (ML603_00735) comGF 118149..118589 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  ML603_RS00740 (ML603_00740) comGG 118618..118941 (+) 324 WP_226955945.1 competence type IV pilus minor pilin ComGG -
  ML603_RS00745 (ML603_00745) comYH 119004..119957 (+) 954 WP_192942722.1 class I SAM-dependent methyltransferase Machinery gene
  ML603_RS00750 (ML603_00750) - 120016..121212 (+) 1197 WP_084916957.1 acetate kinase -
  ML603_RS00755 (ML603_00755) - 121518..121724 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38965.39 Da        Isoelectric Point: 9.2055

>NTDB_id=660902 ML603_RS00715 WP_241067698.1 116153..117184(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLTEIIAFLTKSHLILEPYVLRMEEALLKGRGLADMLAGLG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLETQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFTHLSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWAQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=660902 ML603_RS00715 WP_241067698.1 116153..117184(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGACCTTCTTGCAACGGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGACTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCTCGAGCCCTATGTTCTTCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGTTAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAACTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACCTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGGCAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGGCTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.839

99.417

0.545
  comYB Streptococcus mutans UA159

54.839

99.417

0.545
  comYB Streptococcus gordonii str. Challis substr. CH1

48.968

98.834

0.484
  comGB/cglB Streptococcus mitis NCTC 12261

46.567

97.668

0.455
  comGB/cglB Streptococcus mitis SK321

45.946

97.085

0.446
  comGB/cglB Streptococcus pneumoniae Rx1

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae D39

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae R6

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae TIGR4

44.444

97.085

0.431
  comGB Lactococcus lactis subsp. cremoris KW2

43.363

98.834

0.429