Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS04460 Genome accession   NZ_CP108130
Coordinates   979049..979747 (-) Length   232 a.a.
NCBI ID   WP_406264428.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 974049..984747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS04435 (OHT93_04390) - 974423..974776 (-) 354 WP_406264418.1 cupin domain-containing protein -
  OHT93_RS04440 (OHT93_04395) - 974966..975931 (+) 966 WP_406264420.1 DUF3048 domain-containing protein -
  OHT93_RS04445 (OHT93_04400) - 976177..977100 (+) 924 WP_406264422.1 glutamate ABC transporter substrate-binding protein -
  OHT93_RS04450 (OHT93_04405) - 977207..977830 (+) 624 WP_406264424.1 NAD(P)-dependent oxidoreductase -
  OHT93_RS04455 (OHT93_04410) - 977874..978893 (-) 1020 WP_406264426.1 zinc-dependent alcohol dehydrogenase family protein -
  OHT93_RS04460 (OHT93_04415) vraR 979049..979747 (-) 699 WP_406264428.1 response regulator Regulator
  OHT93_RS04465 (OHT93_04420) - 979744..980982 (-) 1239 WP_406264430.1 sensor histidine kinase -
  OHT93_RS04470 (OHT93_04425) - 981268..982653 (+) 1386 WP_406264432.1 tannase/feruloyl esterase family alpha/beta hydrolase -
  OHT93_RS04475 (OHT93_04430) - 982663..984048 (-) 1386 WP_406264434.1 FAD-binding oxidoreductase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24313.83 Da        Isoelectric Point: 6.3406

>NTDB_id=654550 OHT93_RS04460 WP_406264428.1 979049..979747(-) (vraR) [Streptomyces sp. NBC_00191]
MSTRPSQTRDSVAVLVVDDQELVREGIASLLSLQPGITVVGAVADGRQAVEAAVTHPPDVILMDVRMPVMDGVEAVAQLS
RRAPTCKVVMLTTFDDDEYVVRALRAGAAGYLLKNLPAAELADAVRLAHAGVTQLDSSVARILTGALLPAEPGRGAGDSA
AASSNGVPLSGLTAREVEVLRLIAAGSTNREIASRLYVSEGTVKNHISRILGRLGLRDRTQAAIYAHDHGLL

Nucleotide


Download         Length: 699 bp        

>NTDB_id=654550 OHT93_RS04460 WP_406264428.1 979049..979747(-) (vraR) [Streptomyces sp. NBC_00191]
ATGAGTACGCGCCCGTCGCAGACCCGCGACAGCGTGGCGGTGCTGGTCGTCGACGACCAGGAGCTGGTGCGGGAGGGGAT
CGCCTCGCTGCTGAGCCTGCAGCCCGGGATCACCGTGGTCGGCGCCGTCGCGGACGGACGACAGGCCGTCGAGGCCGCCG
TGACGCACCCACCCGACGTGATCCTGATGGACGTCCGTATGCCGGTGATGGACGGTGTCGAGGCAGTGGCCCAGCTGAGC
AGACGGGCCCCGACGTGCAAGGTCGTCATGCTGACGACCTTCGACGACGACGAGTACGTGGTGCGGGCACTGCGCGCGGG
GGCGGCGGGCTATCTGCTGAAGAACCTGCCCGCAGCCGAACTGGCCGACGCGGTGCGTCTTGCTCATGCCGGGGTCACCC
AGCTCGACTCCTCGGTGGCCCGGATTCTCACCGGCGCGCTGCTGCCCGCCGAGCCCGGCCGGGGCGCTGGGGACTCGGCC
GCTGCGTCCTCCAACGGCGTTCCTCTCAGCGGTCTGACCGCCCGTGAGGTCGAGGTGCTGCGGCTGATCGCCGCGGGCTC
CACCAACCGTGAGATCGCGTCCCGGCTCTACGTCAGCGAGGGCACCGTCAAGAACCACATCTCACGGATCCTGGGCAGGC
TCGGGCTTCGCGACCGCACCCAGGCGGCGATCTACGCGCACGACCACGGACTCCTCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(172-226)

Response regulator receiver domain (Response_reg)

(14-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.342

95.69

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

98.707

0.379