Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG974_RS23000 Genome accession   NZ_CP107757
Coordinates   5074462..5075142 (-) Length   226 a.a.
NCBI ID   WP_327284559.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00597     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5069462..5080142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG974_RS22975 (OG974_22960) - 5069564..5070760 (-) 1197 WP_371644289.1 cytochrome P450 -
  OG974_RS22980 (OG974_22965) - 5070895..5072061 (+) 1167 WP_328763290.1 delta-60 repeat domain-containing protein -
  OG974_RS22985 (OG974_22970) - 5072080..5072343 (+) 264 WP_327284556.1 hypothetical protein -
  OG974_RS22990 (OG974_22975) vraR 5072366..5073025 (-) 660 WP_327284557.1 response regulator transcription factor Regulator
  OG974_RS22995 (OG974_22980) - 5073022..5074374 (-) 1353 WP_371644291.1 sensor histidine kinase -
  OG974_RS23000 (OG974_22985) vraR 5074462..5075142 (-) 681 WP_327284559.1 response regulator transcription factor Regulator
  OG974_RS23005 (OG974_22990) - 5075152..5076537 (-) 1386 WP_371644293.1 sensor histidine kinase -
  OG974_RS23010 (OG974_22995) - 5076530..5077741 (-) 1212 WP_327284561.1 acyltransferase -
  OG974_RS23015 (OG974_23000) - 5077734..5078753 (-) 1020 WP_327284562.1 alpha/beta hydrolase -
  OG974_RS23020 (OG974_23005) - 5078975..5079490 (+) 516 WP_327284563.1 diadenosine tetraphosphate hydrolase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24084.82 Da        Isoelectric Point: 4.6899

>NTDB_id=645703 OG974_RS23000 WP_327284559.1 5074462..5075142(-) (vraR) [Streptomyces sp. NBC_00597]
MSTPPDPIKVMIADDQMMVRQGFTVLLNAQPDIRVVGQAVDGADAVAKVAELGPDVVLMDIRMPGMGGIEATSIITATPD
STVKVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLAEAVRVVAAGEALLSPNITKRLITEFSRMGAPRAPSKARIDE
LTERETEVLSLIAQGLSNAEIAGHLVVAEQTVKTHVGRILVKLGLRDRTQAAVFAYETGLVRPTGY

Nucleotide


Download         Length: 681 bp        

>NTDB_id=645703 OG974_RS23000 WP_327284559.1 5074462..5075142(-) (vraR) [Streptomyces sp. NBC_00597]
ATGAGCACTCCGCCCGACCCGATCAAGGTGATGATCGCCGACGACCAGATGATGGTCCGGCAGGGCTTCACCGTCCTCCT
CAATGCCCAGCCCGACATCCGGGTCGTCGGGCAGGCCGTGGACGGCGCCGACGCGGTGGCGAAGGTCGCCGAACTCGGCC
CGGACGTGGTGCTGATGGACATCCGCATGCCCGGGATGGGCGGCATCGAGGCCACCTCGATCATCACGGCAACCCCGGAC
TCCACCGTCAAGGTGCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTGTACGAGGCGCTGCGCGCCGGGGCCTCCGG
GTTCCTGCTGAAGGACGCGTCGGCCGACCAACTCGCCGAGGCGGTCCGGGTGGTGGCGGCCGGTGAGGCGCTGCTCTCAC
CGAACATCACGAAACGGCTGATCACCGAGTTCTCCCGGATGGGGGCGCCGCGGGCGCCCTCCAAGGCGCGGATCGACGAG
CTGACCGAGCGGGAGACCGAGGTGCTGTCGCTGATCGCGCAGGGCCTGTCCAACGCGGAGATCGCCGGGCACCTGGTCGT
GGCCGAGCAGACCGTGAAGACCCATGTGGGGCGGATCCTGGTGAAGCTGGGCCTGCGGGACCGCACCCAGGCCGCGGTGT
TCGCGTACGAGACGGGTCTCGTCCGTCCGACGGGCTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-123)

Bacterial regulatory proteins, luxR family (GerE)

(160-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.779

96.018

0.42
  degU Bacillus subtilis subsp. subtilis str. 168

41.333

99.558

0.412