Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   SIR_RS18225 Genome accession   NC_022246
Coordinates   1759929..1760246 (-) Length   105 a.a.
NCBI ID   WP_003075998.1    Uniprot ID   A0AAE8G310
Organism   Streptococcus intermedius B196     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1754929..1765246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS18195 (SIR_1661) - 1756258..1757457 (-) 1200 WP_021003254.1 acetate kinase -
  SIR_RS18200 (SIR_1662) comYH 1757504..1758457 (-) 954 WP_021003255.1 class I SAM-dependent methyltransferase Machinery gene
  SIR_RS18205 (SIR_1663) comGG 1758548..1758874 (-) 327 WP_021003256.1 competence type IV pilus minor pilin ComGG -
  SIR_RS18210 (SIR_1664) comGF/cglF 1758855..1759292 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SIR_RS18215 (SIR_1665) comGE/cglE 1759276..1759569 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  SIR_RS18220 (SIR_1666) comYD 1759541..1759969 (-) 429 WP_021003257.1 competence type IV pilus minor pilin ComGD Machinery gene
  SIR_RS18225 (SIR_1667) comYC 1759929..1760246 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SIR_RS18230 (SIR_1668) comYB 1760243..1761265 (-) 1023 WP_021003258.1 competence type IV pilus assembly protein ComGB Machinery gene
  SIR_RS18235 (SIR_1669) comYA 1761207..1762148 (-) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  SIR_RS18240 (SIR_1670) - 1762217..1762582 (-) 366 WP_021003259.1 DUF1033 family protein -
  SIR_RS18245 (SIR_1671) glnA 1762804..1764150 (-) 1347 WP_021003260.1 type I glutamate--ammonia ligase -
  SIR_RS18250 (SIR_1672) - 1764189..1764548 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  SIR_RS18255 (SIR_1673) - 1764625..1765155 (-) 531 WP_009569519.1 FUSC family protein -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11666.77 Da        Isoelectric Point: 10.1006

>NTDB_id=61915 SIR_RS18225 WP_003075998.1 1759929..1760246(-) (comYC) [Streptococcus intermedius B196]
MKKIKNLKVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHSNEKATLSKLVTEGT
ITDKQAASYKAYYAKHTKETRSVAD

Nucleotide


Download         Length: 318 bp        

>NTDB_id=61915 SIR_RS18225 WP_003075998.1 1759929..1760246(-) (comYC) [Streptococcus intermedius B196]
GTGAAAAAAATTAAAAATTTAAAGGTTAAAGCTTTTACTTTAGTGGAAATGTTGGTCGTGCTTTTAATTATTAGTGTTTT
AATGCTCTTATTTGTGCCGAATTTGACCAAGCAAAAGGAAGCAGTAACAGAAAAAGGAAATGCAGCTGTGGTCAAAGTTG
TAGAGAGCCAAGCGGAACTTTTTGAGGTCAATCATAGCAATGAAAAAGCAACGCTTTCAAAATTAGTCACTGAAGGCACG
ATTACAGATAAGCAGGCAGCGTCATATAAGGCTTACTATGCGAAACATACAAAAGAAACTCGTTCTGTTGCAGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

73.333

100

0.733

  comYC Streptococcus mutans UA140

68.571

100

0.686

  comYC Streptococcus mutans UA159

68.571

100

0.686

  comGC/cglC Streptococcus mitis NCTC 12261

68.627

97.143

0.667

  comGC/cglC Streptococcus mitis SK321

68.627

97.143

0.667

  comGC/cglC Streptococcus pneumoniae Rx1

66.667

97.143

0.648

  comGC/cglC Streptococcus pneumoniae D39

66.667

97.143

0.648

  comGC/cglC Streptococcus pneumoniae TIGR4

66.667

97.143

0.648

  comGC/cglC Streptococcus pneumoniae R6

66.667

97.143

0.648

  comGC Lactococcus lactis subsp. cremoris KW2

54.808

99.048

0.543

  comYC Streptococcus suis isolate S10

64.045

84.762

0.543


Multiple sequence alignment