Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   GDK18_RS10905 Genome accession   NZ_AP019543
Coordinates   2147623..2148336 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain KG-18     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2142623..2153336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GDK18_RS10845 (SAKG18_19840) - 2143824..2144087 (-) 264 WP_001205732.1 hypothetical protein -
  GDK18_RS10850 (SAKG18_19850) - 2144096..2144356 (-) 261 WP_000291510.1 DUF1108 family protein -
  GDK18_RS10855 (SAKG18_19860) - 2144361..2144663 (-) 303 WP_000165371.1 DUF2482 family protein -
  GDK18_RS10860 (SAKG18_19870) - 2144758..2144919 (-) 162 WP_000048129.1 DUF1270 family protein -
  GDK18_RS10865 (SAKG18_19880) - 2144916..2145239 (-) 324 WP_001120201.1 DUF771 domain-containing protein -
  GDK18_RS10870 (SAKG18_19890) - 2145294..2145674 (+) 381 WP_000762521.1 DUF2513 domain-containing protein -
  GDK18_RS10875 (SAKG18_19900) - 2145661..2145858 (-) 198 WP_001148856.1 hypothetical protein -
  GDK18_RS10880 (SAKG18_19910) - 2145874..2146626 (-) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  GDK18_RS10885 (SAKG18_19920) - 2146677..2147006 (+) 330 WP_000128909.1 hypothetical protein -
  GDK18_RS10890 (SAKG18_19930) - 2146995..2147210 (-) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  GDK18_RS10895 (SAKG18_19940) - 2147226..2147489 (-) 264 Protein_2072 helix-turn-helix transcriptional regulator -
  GDK18_RS10900 - 2147486..2147660 (-) 175 Protein_2073 transcriptional regulator -
  GDK18_RS10905 (SAKG18_19950) irvR 2147623..2148336 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  GDK18_RS10910 (SAKG18_19960) - 2148352..2149284 (+) 933 WP_000759682.1 exonuclease domain-containing protein -
  GDK18_RS10915 (SAKG18_19970) - 2149290..2149631 (+) 342 WP_000591749.1 hypothetical protein -
  GDK18_RS10920 (SAKG18_19980) - 2149835..2150017 (+) 183 WP_000694772.1 hypothetical protein -
  GDK18_RS10925 (SAKG18_19990) - 2150117..2151100 (+) 984 WP_001558608.1 glycosyltransferase family 2 protein -
  GDK18_RS10930 (SAKG18_20000) - 2151111..2151353 (+) 243 WP_000427213.1 hypothetical protein -
  GDK18_RS10935 (SAKG18_20010) - 2151416..2152453 (+) 1038 WP_000857180.1 site-specific integrase -
  GDK18_RS10940 (SAKG18_20020) sph 2152504..2153334 (+) 831 Protein_2081 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=61916 GDK18_RS10905 WP_001031454.1 2147623..2148336(+) (irvR) [Staphylococcus aureus strain KG-18]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=61916 GDK18_RS10905 WP_001031454.1 2147623..2148336(+) (irvR) [Staphylococcus aureus strain KG-18]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401

Multiple sequence alignment