Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SIR_RS18215 Genome accession   NC_022246
Coordinates   1759276..1759569 (-) Length   97 a.a.
NCBI ID   WP_003073987.1    Uniprot ID   -
Organism   Streptococcus intermedius B196     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1754276..1764569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS18195 (SIR_1661) - 1756258..1757457 (-) 1200 WP_021003254.1 acetate kinase -
  SIR_RS18200 (SIR_1662) comYH 1757504..1758457 (-) 954 WP_021003255.1 class I SAM-dependent methyltransferase Machinery gene
  SIR_RS18205 (SIR_1663) comGG 1758548..1758874 (-) 327 WP_021003256.1 competence type IV pilus minor pilin ComGG -
  SIR_RS18210 (SIR_1664) comGF/cglF 1758855..1759292 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SIR_RS18215 (SIR_1665) comGE/cglE 1759276..1759569 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  SIR_RS18220 (SIR_1666) comYD 1759541..1759969 (-) 429 WP_021003257.1 competence type IV pilus minor pilin ComGD Machinery gene
  SIR_RS18225 (SIR_1667) comYC 1759929..1760246 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SIR_RS18230 (SIR_1668) comYB 1760243..1761265 (-) 1023 WP_021003258.1 competence type IV pilus assembly protein ComGB Machinery gene
  SIR_RS18235 (SIR_1669) comYA 1761207..1762148 (-) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  SIR_RS18240 (SIR_1670) - 1762217..1762582 (-) 366 WP_021003259.1 DUF1033 family protein -
  SIR_RS18245 (SIR_1671) glnA 1762804..1764150 (-) 1347 WP_021003260.1 type I glutamate--ammonia ligase -
  SIR_RS18250 (SIR_1672) - 1764189..1764548 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11195.24 Da        Isoelectric Point: 10.4670

>NTDB_id=61913 SIR_RS18215 WP_003073987.1 1759276..1759569(-) (comGE/cglE) [Streptococcus intermedius B196]
MENLRKQYVRGTILLEALLALAIFATIVTLLLGQIHQSRKLENELLKKEEVLRVAKMALQTNQRHLTMNGIEVRVEKSQQ
DIRVYHGKELIFGVQSK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=61913 SIR_RS18215 WP_003073987.1 1759276..1759569(-) (comGE/cglE) [Streptococcus intermedius B196]
ATGGAAAATTTAAGAAAACAATATGTTAGAGGGACAATTTTATTAGAAGCACTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTAACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAACTAGAAAATGAGTTATTGAAAAAAGAAGAAGTCTTAAGGG
TAGCGAAGATGGCCTTGCAAACAAATCAAAGGCATTTAACAATGAACGGTATTGAAGTACGTGTCGAAAAAAGCCAACAA
GATATTCGGGTTTATCATGGGAAGGAGCTGATTTTTGGTGTTCAAAGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-91)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comYE Streptococcus mutans UA140

48.352

93.814

0.454
  comYE Streptococcus mutans UA159

48.352

93.814

0.454

Multiple sequence alignment