Detailed information NTG0061733

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: SAIN_RS00985
• Genome accession: NC_022244
• Coordinates: 195055..195372 (+)
• Length: 105 a.a.
• NCBI ID: WP_003028473.1
• Uniprot ID: A0A0P0N5S2
• Organism: Streptococcus anginosus C1051
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 190055..200372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAIN_RS00955 (SAIN_0189)	-	190178..190708 (+)	531	WP_003032280.1	FUSC family protein	-
SAIN_RS00960 (SAIN_0190)	-	190785..191144 (+)	360	WP_003028467.1	MerR family transcriptional regulator	-
SAIN_RS00965 (SAIN_0191)	glnA	191183..192529 (+)	1347	WP_003027006.1	type I glutamate--ammonia ligase	-
SAIN_RS00970 (SAIN_0192)	-	192718..193083 (+)	366	WP_003027003.1	DUF1033 family protein	-
SAIN_RS00975 (SAIN_0193)	comYA	193153..194094 (+)	942	WP_003027001.1	competence type IV pilus ATPase ComGA	Machinery gene
SAIN_RS00980 (SAIN_0194)	comYB	194036..195058 (+)	1023	WP_041783985.1	competence type IV pilus assembly protein ComGB	Machinery gene
SAIN_RS00985 (SAIN_0195)	comYC	195055..195372 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
SAIN_RS00990 (SAIN_0196)	comYD	195332..195760 (+)	429	WP_021001232.1	competence type IV pilus minor pilin ComGD	Machinery gene
SAIN_RS00995 (SAIN_0197)	comGE/cglE	195732..196025 (+)	294	WP_021001233.1	competence type IV pilus minor pilin ComGE	Machinery gene
SAIN_RS01000	comGF/cglF	196009..196446 (+)	438	WP_041783987.1	competence type IV pilus minor pilin ComGF	Machinery gene
SAIN_RS01005 (SAIN_0198)	comGG	196427..196753 (+)	327	WP_021001234.1	competence type IV pilus minor pilin ComGG	-
SAIN_RS01010 (SAIN_0199)	comYH	196825..197778 (+)	954	WP_021001235.1	class I SAM-dependent methyltransferase	Machinery gene
SAIN_RS01015 (SAIN_0200)	-	197825..199024 (+)	1200	WP_021001236.1	acetate kinase	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11622.72 Da
• Isoelectric Point: 10.1006

>NTDB_id=61733 SAIN_RS00985 WP_003028473.1 195055..195372(+) (comYC) [Streptococcus anginosus C1051]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=61733 SAIN_RS00985 WP_003028473.1 195055..195372(+) (comYC) [Streptococcus anginosus C1051]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAAATGTTAGTCGTACTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAAGCGGAGCTGTTTGAGGTCAATCACACCAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGCACG
ATTACAGACAAGCAGGCAGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCTGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0P0N5S2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comYC	Streptococcus mutans UA159	66.667	100	0.667
comYC	Streptococcus mutans UA140	66.667	100	0.667
comGC/cglC	Streptococcus mitis NCTC 12261	68.627	97.143	0.667
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543