Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SAIN_RS00995 Genome accession   NC_022244
Coordinates   195732..196025 (+) Length   97 a.a.
NCBI ID   WP_021001233.1    Uniprot ID   -
Organism   Streptococcus anginosus C1051     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 190732..201025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAIN_RS00960 (SAIN_0190) - 190785..191144 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SAIN_RS00965 (SAIN_0191) glnA 191183..192529 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  SAIN_RS00970 (SAIN_0192) - 192718..193083 (+) 366 WP_003027003.1 DUF1033 family protein -
  SAIN_RS00975 (SAIN_0193) comYA 193153..194094 (+) 942 WP_003027001.1 competence type IV pilus ATPase ComGA Machinery gene
  SAIN_RS00980 (SAIN_0194) comYB 194036..195058 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  SAIN_RS00985 (SAIN_0195) comYC 195055..195372 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  SAIN_RS00990 (SAIN_0196) comYD 195332..195760 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  SAIN_RS00995 (SAIN_0197) comGE/cglE 195732..196025 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  SAIN_RS01000 comGF/cglF 196009..196446 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  SAIN_RS01005 (SAIN_0198) comGG 196427..196753 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG -
  SAIN_RS01010 (SAIN_0199) comYH 196825..197778 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  SAIN_RS01015 (SAIN_0200) - 197825..199024 (+) 1200 WP_021001236.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10809.73 Da        Isoelectric Point: 10.2047

>NTDB_id=61735 SAIN_RS00995 WP_021001233.1 195732..196025(+) (comGE/cglE) [Streptococcus anginosus C1051]
MGNLRKQHVKGTILLEALLALAVFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIEVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=61735 SAIN_RS00995 WP_021001233.1 195732..196025(+) (comGE/cglE) [Streptococcus anginosus C1051]
ATGGGAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAAACAAAGCAAAGTCATCTGACAATGAACGGTATTGAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAGATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae D39

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae R6

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae TIGR4

52.632

97.938

0.515
  comGE/cglE Streptococcus mitis NCTC 12261

51.579

97.938

0.505
  comGE/cglE Streptococcus mitis SK321

51.579

97.938

0.505
  comYE Streptococcus mutans UA140

44.444

100

0.454
  comYE Streptococcus mutans UA159

44.444

100

0.454

Multiple sequence alignment