Detailed information NTG0061736

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SAIN_RS01000
• Genome accession: NC_022244
• Coordinates: 196009..196446 (+)
• Length: 145 a.a.
• NCBI ID: WP_041783987.1
• Uniprot ID: A0AAP6EPH2
• Organism: Streptococcus anginosus C1051
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 191009..201446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAIN_RS00965 (SAIN_0191)	glnA	191183..192529 (+)	1347	WP_003027006.1	type I glutamate--ammonia ligase	-
SAIN_RS00970 (SAIN_0192)	-	192718..193083 (+)	366	WP_003027003.1	DUF1033 family protein	-
SAIN_RS00975 (SAIN_0193)	comYA	193153..194094 (+)	942	WP_003027001.1	competence type IV pilus ATPase ComGA	Machinery gene
SAIN_RS00980 (SAIN_0194)	comYB	194036..195058 (+)	1023	WP_041783985.1	competence type IV pilus assembly protein ComGB	Machinery gene
SAIN_RS00985 (SAIN_0195)	comYC	195055..195372 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
SAIN_RS00990 (SAIN_0196)	comYD	195332..195760 (+)	429	WP_021001232.1	competence type IV pilus minor pilin ComGD	Machinery gene
SAIN_RS00995 (SAIN_0197)	comGE/cglE	195732..196025 (+)	294	WP_021001233.1	competence type IV pilus minor pilin ComGE	Machinery gene
SAIN_RS01000	comGF/cglF	196009..196446 (+)	438	WP_041783987.1	competence type IV pilus minor pilin ComGF	Machinery gene
SAIN_RS01005 (SAIN_0198)	comGG	196427..196753 (+)	327	WP_021001234.1	competence type IV pilus minor pilin ComGG	-
SAIN_RS01010 (SAIN_0199)	comYH	196825..197778 (+)	954	WP_021001235.1	class I SAM-dependent methyltransferase	Machinery gene
SAIN_RS01015 (SAIN_0200)	-	197825..199024 (+)	1200	WP_021001236.1	acetate kinase	-
SAIN_RS01020 (SAIN_0201)	glmS	199376..201190 (+)	1815	WP_003026983.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16769.29 Da
• Isoelectric Point: 10.0941

>NTDB_id=61736 SAIN_RS01000 WP_041783987.1 196009..196446(+) (comGF/cglF) [Streptococcus anginosus C1051]
MFKANKVKAFTLLEALIALFVISGSVLLFQSMTRLLASEVQARQHSEQREWLLFADQLEAELARSSFEKVENNRLYMKQD
GKVIAFGKSSGQDFRKTNANGKGYQPMVYDVKKAEISQKNELIHVRLTFRRGLEREFVYRVETES

Nucleotide

• Length: 438 bp

>NTDB_id=61736 SAIN_RS01000 WP_041783987.1 196009..196446(+) (comGF/cglF) [Streptococcus anginosus C1051]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACCCTTTTAGAGGCTCTGATTGCCCTCTTTGTCATTAGTGGAAGTGTGTT
GCTGTTTCAATCTATGACGCGCCTTCTAGCTTCTGAAGTCCAAGCTCGTCAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCAGATCAACTAGAAGCAGAGTTGGCTCGTTCTTCATTTGAAAAGGTGGAGAATAATCGTTTATATATGAAACAGGAC
GGCAAGGTGATTGCATTTGGAAAGTCAAGTGGACAGGATTTCAGAAAAACCAATGCGAATGGGAAAGGTTACCAGCCGAT
GGTTTATGATGTAAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATGTTAGACTGACGTTTAGGCGAGGATTGG
AAAGGGAGTTTGTCTATCGTGTGGAAACAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	66.901	97.931	0.655
comGF/cglF	Streptococcus pneumoniae TIGR4	66.901	97.931	0.655
comGF/cglF	Streptococcus pneumoniae Rx1	66.901	97.931	0.655
comGF/cglF	Streptococcus pneumoniae D39	66.901	97.931	0.655
comGF/cglF	Streptococcus mitis NCTC 12261	67.143	96.552	0.648
comGF/cglF	Streptococcus mitis SK321	67.143	96.552	0.648
comYF	Streptococcus mutans UA159	45.185	93.103	0.421
comYF	Streptococcus mutans UA140	45.185	93.103	0.421
comGF	Lactococcus lactis subsp. cremoris KW2	42.222	93.103	0.393