Detailed information NTG0061696

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: SANR_RS10920
• Genome accession: NC_022239
• Coordinates: 2228434..2229183 (-)
• Length: 249 a.a.
• NCBI ID: WP_003038257.1
• Uniprot ID: -
• Organism: Streptococcus anginosus C238
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2223434..2234183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS10900 (SANR_2117)	-	2223815..2225437 (+)	1623	WP_003038260.1	ATP-binding cassette domain-containing protein	-
SANR_RS10905 (SANR_2118)	-	2225511..2228087 (+)	2577	WP_004225037.1	YfhO family protein	-
SANR_RS10920 (SANR_2121)	comE/comE2	2228434..2229183 (-)	750	WP_003038257.1	competence system response regulator transcription factor ComE	Regulator
SANR_RS10925 (SANR_2122)	comD/comD2	2229183..2230505 (-)	1323	WP_003038254.1	GHKL domain-containing protein	Regulator
SANR_RS11380 (SANR_2123)	-	2230520..2230669 (-)	150	WP_003038250.1	bacteriocin	-
SANR_RS10940	rlmH	2230951..2231430 (-)	480	WP_004225060.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SANR_RS10945 (SANR_2125)	htrA	2231624..2232814 (+)	1191	WP_003032033.1	S1C family serine protease	Regulator
SANR_RS10950 (SANR_2126)	spo0J	2232869..2233636 (+)	768	WP_003038259.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29216.88 Da
• Isoelectric Point: 8.6042

>NTDB_id=61696 SANR_RS10920 WP_003038257.1 2228434..2229183(-) (comE/comE2) [Streptococcus anginosus C238]
MKVLVLEDEITHQVRMETTLAEIAKEMGITIKVKVTGKVREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLSDVAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETRRFFSPHKSYLVNIGNIKGYDKKMREIIFYEDHRCPITRMKLGKL
KAILEELKG

Nucleotide

• Length: 750 bp

>NTDB_id=61696 SANR_RS10920 WP_003038257.1 2228434..2229183(-) (comE/comE2) [Streptococcus anginosus C238]
ATGAAAGTATTAGTATTAGAAGATGAAATTACACATCAAGTAAGAATGGAAACAACTTTGGCAGAGATTGCAAAAGAAAT
GGGAATTACGATAAAAGTTAAAGTAACTGGAAAAGTAAGGGAATTTAAAGAATATATTGAAAACGATGAAGTAAATCAAT
TATATTTTTTAGATATTGATATTAAAGGAGAGGAAACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCACAATCCG
TATGCCATTATTGTTTTTGTTACAACGAAATCAGAATTTGCCACTATGACCTTCAAATATAAGGTATCTGCACTGGATTT
TGTTGATAAAAATTTGAGTGATGTTGCTTTTAAAAAACATATAAAAGACAGCATTGAGTATACAAAAGCGACATTGATTG
AAAATAAAGATATGGTGGATTATTTTGAATATAGCTTTCGTGGCGGAGAGGTTAGAATGCCTTTTAATGACATTTTATAT
ATTGAAACGACAGGCTCTTCTCATAAATTAAGAATTGTCGGTAAAAACTTTTTTAAAGAATTCTATGGCACTATTGCAGA
TATTCAAGAAAAAGATAAAGAAACAAGACGTTTCTTTTCACCTCATAAATCCTACCTAGTCAATATTGGAAACATCAAAG
GTTATGACAAAAAAATGCGAGAAATAATTTTTTATGAAGATCATCGTTGTCCGATTACTCGAATGAAACTTGGAAAATTA
AAAGCTATTTTAGAGGAATTAAAAGGATAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-244)

• Response regulator receiver domain (Response_reg) (3-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus gordonii strain NCTC7865	70.492	97.992	0.691
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	70.492	97.992	0.691
comE	Streptococcus mitis NCTC 12261	70.204	98.394	0.691
comE	Streptococcus infantis strain Atu-4	69.796	98.394	0.687
comE	Streptococcus mitis SK321	69.388	98.394	0.683
comE	Streptococcus pneumoniae Rx1	68.98	98.394	0.679
comE	Streptococcus pneumoniae D39	68.98	98.394	0.679
comE	Streptococcus pneumoniae R6	68.98	98.394	0.679
comE	Streptococcus pneumoniae TIGR4	68.98	98.394	0.679
comE/blpR	Streptococcus mutans UA159	40.891	99.197	0.406