Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   KE3_RS00245 Genome accession   NC_021900
Coordinates   49849..50142 (+) Length   97 a.a.
NCBI ID   WP_020915989.1    Uniprot ID   -
Organism   Streptococcus lutetiensis 033     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 44849..55142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS00230 (KE3_0048) - 47501..47869 (+) 369 WP_020915986.1 DUF1033 family protein -
  KE3_RS00235 (KE3_0049) comYA 47941..48882 (+) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  KE3_RS00240 (KE3_0050) comYB 48806..49849 (+) 1044 WP_020915988.1 competence type IV pilus assembly protein ComGB Machinery gene
  KE3_RS00245 (KE3_0051) comYC 49849..50142 (+) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  KE3_RS00250 (KE3_0052) comYD 50126..50557 (+) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  KE3_RS00255 (KE3_0053) comYE 50511..50804 (+) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  KE3_RS00260 (KE3_0054) comYF 50788..51225 (+) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  KE3_RS00265 (KE3_0055) comGG 51197..51547 (+) 351 WP_020915993.1 competence type IV pilus minor pilin ComGG -
  KE3_RS00270 (KE3_0056) comYH 51601..52557 (+) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  KE3_RS00275 (KE3_0057) - 52611..53810 (+) 1200 WP_020915995.1 acetate kinase -
  KE3_RS00280 (KE3_0058) - 53970..54167 (+) 198 WP_020915996.1 helix-turn-helix transcriptional regulator -
  KE3_RS00285 (KE3_0059) - 54184..54384 (+) 201 WP_020915997.1 hypothetical protein -
  KE3_RS00290 (KE3_0060) - 54385..54840 (+) 456 WP_020915998.1 hypothetical protein -

Sequence


Protein


Download         Length: 97 a.a.        Molecular weight: 11018.16 Da        Isoelectric Point: 10.1006

>NTDB_id=60798 KE3_RS00245 WP_020915989.1 49849..50142(+) (comYC) [Streptococcus lutetiensis 033]
MKNIWKKLRKKSVEAFTLVEMLIVLLIIGVLMLLFVPNLSKQKEVVHEKGDAAVVKVVESQMELYEVKTGKQPTVNDLVK
AEYISKDQAQTYNAAKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=60798 KE3_RS00245 WP_020915989.1 49849..50142(+) (comYC) [Streptococcus lutetiensis 033]
ATGAAAAACATTTGGAAAAAACTACGTAAAAAGTCTGTAGAAGCTTTTACACTTGTGGAGATGTTGATTGTTTTGCTAAT
CATTGGTGTCTTGATGCTGTTATTTGTGCCAAACTTGAGCAAGCAAAAAGAGGTTGTGCATGAAAAAGGAGATGCTGCTG
TTGTCAAAGTTGTCGAAAGTCAGATGGAGCTTTATGAAGTGAAGACAGGTAAACAACCAACTGTAAATGATTTGGTGAAA
GCTGAATATATTTCAAAAGACCAAGCTCAAACATATAATGCGGCTAAAAAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

68.539

91.753

0.629

  comYC Streptococcus suis isolate S10

60.87

94.845

0.577

  comGC/cglC Streptococcus mitis SK321

56.989

95.876

0.546

  comGC/cglC Streptococcus pneumoniae Rx1

56.522

94.845

0.536

  comGC/cglC Streptococcus pneumoniae D39

56.522

94.845

0.536

  comGC/cglC Streptococcus pneumoniae R6

56.522

94.845

0.536

  comGC/cglC Streptococcus pneumoniae TIGR4

56.522

94.845

0.536

  comGC/cglC Streptococcus mitis NCTC 12261

56.522

94.845

0.536

  comYC Streptococcus mutans UA140

56.322

89.691

0.505

  comYC Streptococcus mutans UA159

56.322

89.691

0.505

  comGC Lactococcus lactis subsp. cremoris KW2

51.685

91.753

0.474

  comGC Latilactobacillus sakei subsp. sakei 23K

45.57

81.443

0.371


Multiple sequence alignment