Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   KE3_RS00255 Genome accession   NC_021900
Coordinates   50511..50804 (+) Length   97 a.a.
NCBI ID   WP_020915991.1    Uniprot ID   -
Organism   Streptococcus lutetiensis 033     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 45511..55804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS00230 (KE3_0048) - 47501..47869 (+) 369 WP_020915986.1 DUF1033 family protein -
  KE3_RS00235 (KE3_0049) comYA 47941..48882 (+) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  KE3_RS00240 (KE3_0050) comYB 48806..49849 (+) 1044 WP_020915988.1 competence type IV pilus assembly protein ComGB Machinery gene
  KE3_RS00245 (KE3_0051) comYC 49849..50142 (+) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  KE3_RS00250 (KE3_0052) comYD 50126..50557 (+) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  KE3_RS00255 (KE3_0053) comYE 50511..50804 (+) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  KE3_RS00260 (KE3_0054) comYF 50788..51225 (+) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  KE3_RS00265 (KE3_0055) comGG 51197..51547 (+) 351 WP_020915993.1 competence type IV pilus minor pilin ComGG -
  KE3_RS00270 (KE3_0056) comYH 51601..52557 (+) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  KE3_RS00275 (KE3_0057) - 52611..53810 (+) 1200 WP_020915995.1 acetate kinase -
  KE3_RS00280 (KE3_0058) - 53970..54167 (+) 198 WP_020915996.1 helix-turn-helix transcriptional regulator -
  KE3_RS00285 (KE3_0059) - 54184..54384 (+) 201 WP_020915997.1 hypothetical protein -
  KE3_RS00290 (KE3_0060) - 54385..54840 (+) 456 WP_020915998.1 hypothetical protein -
  KE3_RS00295 (KE3_0061) - 54855..55490 (+) 636 WP_043894885.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10823.60 Da        Isoelectric Point: 6.4795

>NTDB_id=60800 KE3_RS00255 WP_020915991.1 50511..50804(+) (comYE) [Streptococcus lutetiensis 033]
MVTIKKQKLKAYILLEGLVALALLATIISLVLGEMDRSRTQMQESLHQQEVLNVATMAVQTGQDHLAINGVEVRMVKHDN
EISVYDGQNEVLHVTKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=60800 KE3_RS00255 WP_020915991.1 50511..50804(+) (comYE) [Streptococcus lutetiensis 033]
GTGGTAACTATAAAAAAACAGAAACTAAAAGCTTACATACTCCTTGAGGGCTTGGTAGCTCTTGCTTTATTAGCAACGAT
TATCAGTCTGGTCTTAGGAGAAATGGACCGTAGTCGCACTCAAATGCAAGAGAGTTTGCATCAGCAAGAAGTACTTAATG
TAGCGACCATGGCCGTTCAAACAGGACAAGACCATTTGGCCATTAATGGGGTTGAGGTGCGTATGGTTAAGCATGATAAT
GAGATTTCCGTTTATGATGGGCAAAATGAGGTGCTGCATGTCACGAAAAATTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

51.042

98.969

0.505
  comYE Streptococcus mutans UA159

51.042

98.969

0.505
  comGE/cglE Streptococcus pneumoniae Rx1

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae D39

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae R6

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

42.391

94.845

0.402
  comGE/cglE Streptococcus mitis SK321

41.304

94.845

0.392
  comGE/cglE Streptococcus mitis NCTC 12261

41.304

94.845

0.392

Multiple sequence alignment