Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   K6976_RS00755 Genome accession   NZ_CP082202
Coordinates   121531..122481 (+) Length   316 a.a.
NCBI ID   WP_222759613.1    Uniprot ID   -
Organism   Streptococcus suis strain SS389     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 116531..127481
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS00745 (K6976_00745) - 120093..120467 (+) 375 WP_024385120.1 DUF1033 family protein -
  K6976_RS00750 (K6976_00750) - 120495..121445 (-) 951 WP_222759611.1 S66 peptidase family protein -
  K6976_RS00755 (K6976_00755) comYA 121531..122481 (+) 951 WP_222759613.1 competence type IV pilus ATPase ComGA Machinery gene
  K6976_RS00760 (K6976_00760) comYB 122393..123430 (+) 1038 WP_261988003.1 competence type IV pilus assembly protein ComGB Machinery gene
  K6976_RS00765 (K6976_00765) comYC 123432..123713 (+) 282 WP_222759615.1 competence type IV pilus major pilin ComGC Machinery gene
  K6976_RS00770 (K6976_00770) comGD 123694..124101 (+) 408 WP_222759617.1 competence type IV pilus minor pilin ComGD -
  K6976_RS00775 (K6976_00775) comYE 124073..124366 (+) 294 WP_172099849.1 competence type IV pilus minor pilin ComGE Machinery gene
  K6976_RS00780 (K6976_00780) comGF/cglF 124353..124787 (+) 435 WP_222759618.1 competence type IV pilus minor pilin ComGF Machinery gene
  K6976_RS00785 (K6976_00785) comGG 124765..125283 (+) 519 WP_222759619.1 competence type IV pilus minor pilin ComGG -
  K6976_RS00790 (K6976_00790) comYH 125337..126290 (+) 954 WP_222759621.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35465.26 Da        Isoelectric Point: 5.2914

>NTDB_id=599861 K6976_RS00755 WP_222759613.1 121531..122481(+) (comYA) [Streptococcus suis strain SS389]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDLAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFANENYQNHSADQWNGQIDRLFAAGHISLRQAETEKIALSSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=599861 K6976_RS00755 WP_222759613.1 121531..122481(+) (comYA) [Streptococcus suis strain SS389]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGGCTATCAAGTCTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAAGAAGTAATAGCCA
TTATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGTAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGACCAGACTTGCTCATCATTGGTGAGATTCGGGATGCGGAAACTG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTTTCAACAGTTCATGCAAGGTCTATTTCAGGAGTCTAT
GCTCGTATGTTAGAACTAGGTGTCAGCCCTGAGGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGTTTGATCGG
GGGAGGAGGTGTAGTGGATTTTGCAAACGAAAACTACCAAAACCATTCCGCAGACCAGTGGAATGGGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTAGTTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

66.881

98.418

0.658
  comYA Streptococcus mutans UA140

66.881

98.418

0.658
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.176

99.051

0.646
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.176

99.051

0.646
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.176

99.051

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.176

99.051

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.176

99.051

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

52.997

100

0.532
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361