Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   TL13_RS00780 Genome accession   NC_021213
Coordinates   126508..127458 (+) Length   316 a.a.
NCBI ID   WP_015646270.1    Uniprot ID   -
Organism   Streptococcus suis TL13     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121508..132458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS00770 (TL13_0153) - 125072..125437 (+) 366 WP_014637310.1 DUF1033 family protein -
  TL13_RS00775 (TL13_0154) - 125472..126422 (-) 951 WP_014637311.1 S66 peptidase family protein -
  TL13_RS00780 (TL13_0155) comYA 126508..127458 (+) 951 WP_015646270.1 competence type IV pilus ATPase ComGA Machinery gene
  TL13_RS00785 (TL13_0156) comYB 127370..128407 (+) 1038 WP_051089044.1 competence type IV pilus assembly protein ComGB Machinery gene
  TL13_RS00790 (TL13_0157) comYC 128409..128690 (+) 282 WP_015646272.1 competence type IV pilus major pilin ComGC Machinery gene
  TL13_RS00795 (TL13_0158) comGD 128671..129078 (+) 408 WP_015646273.1 competence type IV pilus minor pilin ComGD -
  TL13_RS00800 (TL13_0159) comYE 129050..129343 (+) 294 WP_024401507.1 competence type IV pilus minor pilin ComGE Machinery gene
  TL13_RS00805 (TL13_0160) comGF/cglF 129330..129764 (+) 435 WP_015646275.1 competence type IV pilus minor pilin ComGF Machinery gene
  TL13_RS00810 (TL13_0161) comGG 129742..130155 (+) 414 WP_015646276.1 competence type IV pilus minor pilin ComGG -
  TL13_RS00815 (TL13_0162) - 131334..132008 (-) 675 WP_015646277.1 head maturation protease, ClpP-related -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35468.37 Da        Isoelectric Point: 5.6994

>NTDB_id=58607 TL13_RS00780 WP_015646270.1 126508..127458(+) (comYA) [Streptococcus suis TL13]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGISPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADRWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=58607 TL13_RS00780 WP_015646270.1 126508..127458(+) (comYA) [Streptococcus suis TL13]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCTTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGACCAGACTTGCTCATCATTGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGAGTCTAT
GCCCGTATGTTAGAACTAGGCATCAGCCCTGAGGAGTTAAACAATGCCCTTCAAGGGATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCGGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

98.101

0.633
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment