Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   KQ224_RS07610 Genome accession   NZ_CP076721
Coordinates   1456813..1457763 (+) Length   316 a.a.
NCBI ID   WP_216806335.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1451813..1462763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS07600 (KQ224_07600) - 1455374..1455742 (+) 369 WP_171989702.1 DUF1033 family protein -
  KQ224_RS07605 (KQ224_07605) - 1455775..1456725 (-) 951 WP_216806334.1 S66 peptidase family protein -
  KQ224_RS07610 (KQ224_07610) comYA 1456813..1457763 (+) 951 WP_216806335.1 competence type IV pilus ATPase ComGA Machinery gene
  KQ224_RS07615 (KQ224_07615) comYB 1457675..1458712 (+) 1038 WP_216806336.1 competence type IV pilus assembly protein ComGB Machinery gene
  KQ224_RS07620 (KQ224_07620) comYC 1458714..1458992 (+) 279 WP_216806337.1 competence type IV pilus major pilin ComGC Machinery gene
  KQ224_RS07625 (KQ224_07625) comGD 1458982..1459386 (+) 405 WP_216806338.1 competence type IV pilus minor pilin ComGD -
  KQ224_RS07630 (KQ224_07630) comGE 1459358..1459651 (+) 294 WP_105126461.1 competence type IV pilus minor pilin ComGE -
  KQ224_RS07635 (KQ224_07635) comYF 1459638..1460072 (+) 435 WP_216806339.1 competence type IV pilus minor pilin ComGF Machinery gene
  KQ224_RS07640 (KQ224_07640) comGG 1460050..1460550 (+) 501 WP_216806340.1 competence type IV pilus minor pilin ComGG -
  KQ224_RS07645 (KQ224_07645) comYH 1460570..1461523 (+) 954 WP_024392669.1 class I SAM-dependent methyltransferase Machinery gene
  KQ224_RS07650 (KQ224_07650) - 1461573..1462760 (+) 1188 WP_216806341.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35567.65 Da        Isoelectric Point: 5.9964

>NTDB_id=577594 KQ224_RS07610 WP_216806335.1 1456813..1457763(+) (comYA) [Streptococcus parasuis strain H35]
MIQEKARKMIEEAVVERVSDIYLIPRGENYQVYHRIMDEREYIQELAEDEVMAIISHFKFLAGLNVGEKRRSQQGSCDYN
YVSGEISLRLSTVGDYRGKESLVIRLLYDQNQQLKFWFGALERIAQEIKGRGLYLFSGPVGSGKTTLMYQLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSVAGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSSEKWNEQIECLLAAGHISPRQAETEKIVLGSTA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=577594 KQ224_RS07610 WP_216806335.1 1456813..1457763(+) (comYA) [Streptococcus parasuis strain H35]
ATGATTCAAGAAAAAGCAAGAAAAATGATTGAAGAGGCAGTTGTCGAAAGGGTCAGTGATATTTATTTGATTCCAAGAGG
AGAAAACTACCAAGTCTATCATCGAATAATGGATGAACGGGAATATATTCAAGAATTAGCCGAGGATGAGGTGATGGCCA
TTATTAGCCATTTCAAGTTTTTAGCGGGTTTGAATGTCGGTGAAAAACGGCGTAGCCAGCAAGGCTCTTGTGACTACAAT
TATGTTTCAGGGGAGATTTCCCTTCGGTTATCAACGGTTGGTGATTATCGTGGTAAAGAAAGTTTGGTCATTCGTCTGCT
CTATGATCAAAATCAACAACTTAAATTTTGGTTTGGAGCATTGGAGAGGATTGCTCAAGAAATCAAGGGACGAGGGCTCT
ATCTTTTTTCAGGGCCGGTCGGTTCTGGCAAGACTACACTCATGTACCAGCTGGCGAGATTGAAATTTCCAGATAAGCAA
ATTCTAACTATAGAAGATCCAGTGGAAATCAAGCAGGAAGATATGCTCCAACTCCAGCTCAATGAGGCAATTGGTGCTAC
CTATGATAATCTCATCAAACTATCACTTCGTCATCGACCAGATTTACTGATTATTGGAGAAATTCGAGATGCAGAAACTG
CTCGAGCAGTAATTCGAGCTAGTTTGACAGGGGCAACGGTCTTCTCAACGGTTCATGCTAGAAGTGTTGCTGGTGTCTAT
GCTCGCATGTTAGAGCTGGGTGTAAGTCCTGAAGAATTGAATAATGCTCTTCAAGGAATTGCCTATCAACGATTAATAGG
GGGAGGAGGTGTTGTTGATTTTGCAAAAGGAAACTACCAAAACCATTCCTCGGAGAAGTGGAATGAGCAAATTGAATGCC
TTCTTGCAGCGGGACATATCAGTCCTCGGCAGGCAGAAACAGAAAAAATTGTCCTTGGTTCGACAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

68.167

98.418

0.671
  comYA Streptococcus mutans UA140

68.167

98.418

0.671
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.161

98.101

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.161

98.101

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.161

98.101

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.161

98.101

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.839

98.101

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

54.89

100

0.551
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364