Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   KQ224_RS07645 Genome accession   NZ_CP076721
Coordinates   1460570..1461523 (+) Length   317 a.a.
NCBI ID   WP_024392669.1    Uniprot ID   A0A6L8MX04
Organism   Streptococcus parasuis strain H35     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1455570..1466523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS07605 (KQ224_07605) - 1455775..1456725 (-) 951 WP_216806334.1 S66 peptidase family protein -
  KQ224_RS07610 (KQ224_07610) comYA 1456813..1457763 (+) 951 WP_216806335.1 competence type IV pilus ATPase ComGA Machinery gene
  KQ224_RS07615 (KQ224_07615) comYB 1457675..1458712 (+) 1038 WP_216806336.1 competence type IV pilus assembly protein ComGB Machinery gene
  KQ224_RS07620 (KQ224_07620) comYC 1458714..1458992 (+) 279 WP_216806337.1 competence type IV pilus major pilin ComGC Machinery gene
  KQ224_RS07625 (KQ224_07625) comGD 1458982..1459386 (+) 405 WP_216806338.1 competence type IV pilus minor pilin ComGD -
  KQ224_RS07630 (KQ224_07630) comGE 1459358..1459651 (+) 294 WP_105126461.1 competence type IV pilus minor pilin ComGE -
  KQ224_RS07635 (KQ224_07635) comYF 1459638..1460072 (+) 435 WP_216806339.1 competence type IV pilus minor pilin ComGF Machinery gene
  KQ224_RS07640 (KQ224_07640) comGG 1460050..1460550 (+) 501 WP_216806340.1 competence type IV pilus minor pilin ComGG -
  KQ224_RS07645 (KQ224_07645) comYH 1460570..1461523 (+) 954 WP_024392669.1 class I SAM-dependent methyltransferase Machinery gene
  KQ224_RS07650 (KQ224_07650) - 1461573..1462760 (+) 1188 WP_216806341.1 acetate kinase -
  KQ224_RS07655 (KQ224_07655) - 1463015..1463566 (+) 552 WP_216806342.1 folate family ECF transporter S component -
  KQ224_RS07660 (KQ224_07660) - 1463621..1464877 (+) 1257 WP_216806343.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  KQ224_RS07665 (KQ224_07665) pepA 1464922..1465983 (-) 1062 WP_216806344.1 glutamyl aminopeptidase -
  KQ224_RS07670 (KQ224_07670) - 1466196..1466480 (+) 285 WP_171989715.1 DUF4651 domain-containing protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35610.80 Da        Isoelectric Point: 4.5696

>NTDB_id=577598 KQ224_RS07645 WP_024392669.1 1460570..1461523(+) (comYH) [Streptococcus parasuis strain H35]
MKYEKIEQAYNLLLENVQTIQNQLGTNIYDAMIEQNAAYVAGQHETELVLNNNQVLRELALTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVSTPRVTVLEIGSGTGNLAQTILNASQKELDYLGIEIDDLLIDLSASIADVMGAA
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARPLTPFVYPLQSLQEPEAIQKFMVNFKNWKQENAI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=577598 KQ224_RS07645 WP_024392669.1 1460570..1461523(+) (comYH) [Streptococcus parasuis strain H35]
ATGAAATATGAAAAAATTGAACAGGCCTACAACCTGCTTTTAGAAAATGTACAGACAATTCAAAATCAACTTGGGACCAA
TATTTATGATGCTATGATTGAGCAAAATGCTGCCTATGTAGCTGGTCAACATGAAACCGAACTTGTTCTCAACAACAATC
AAGTCTTGAGAGAATTAGCCTTGACAAAGGAAGAATGGCGTCGTGCTTACCAATTCTTGCTCATTAAAGCTAACCAGACA
GAACCGATGCAGTACAACCATCAGTTCACACCTGACTCTATCGGATTTATCTTATCTTTCCTTGTGGACCAGTTGGTCTC
TACTCCAAGAGTGACGGTTTTGGAAATTGGTTCTGGTACAGGAAACTTAGCTCAGACCATTCTCAACGCCAGCCAGAAGG
AATTAGACTATTTAGGGATTGAAATAGATGACCTCTTGATTGATTTATCGGCTAGTATCGCGGATGTCATGGGAGCAGCT
ATTTCATTTGCTCAGGGAGATGCGGTACGTCCTCAGATTTTGAAAGAAAGCCAAGTGATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGTTATCAGGTAGCTAGTCCAAATGAACATACCTACGCCCATCATTTGCTCA
TGGAACAGTCCCTCAAATATCTGGAAAAAGATGGATTTGCGATTTTACTGGCTCCAAATGATTTATTAACGAGTCCGCAA
AGCGATTTATTAAAAGGTTGGTTACAAGAACAAGCCAATATTGTTGCCATGATTGCCCTGCCGCCAAATCTTTTTGGGAA
GGCTGCCATGGCCAAGTCCATTTTTGTGTTACAAAAGAAAGCTGCCAGACCTTTAACTCCTTTCGTTTATCCTTTGCAAA
GCCTGCAAGAACCAGAAGCGATTCAGAAGTTCATGGTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6L8MX04

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

59.494

99.685

0.593
  comYH Streptococcus mutans UA159

59.177

99.685

0.59