Detailed information NTG0577595

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: KQ224_RS07615
• Genome accession: NZ_CP076721
• Coordinates: 1457675..1458712 (+)
• Length: 345 a.a.
• NCBI ID: WP_216806336.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain H35
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1452675..1463712

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KQ224_RS07600 (KQ224_07600)	-	1455374..1455742 (+)	369	WP_171989702.1	DUF1033 family protein	-
KQ224_RS07605 (KQ224_07605)	-	1455775..1456725 (-)	951	WP_216806334.1	S66 peptidase family protein	-
KQ224_RS07610 (KQ224_07610)	comYA	1456813..1457763 (+)	951	WP_216806335.1	competence type IV pilus ATPase ComGA	Machinery gene
KQ224_RS07615 (KQ224_07615)	comYB	1457675..1458712 (+)	1038	WP_216806336.1	competence type IV pilus assembly protein ComGB	Machinery gene
KQ224_RS07620 (KQ224_07620)	comYC	1458714..1458992 (+)	279	WP_216806337.1	competence type IV pilus major pilin ComGC	Machinery gene
KQ224_RS07625 (KQ224_07625)	comGD	1458982..1459386 (+)	405	WP_216806338.1	competence type IV pilus minor pilin ComGD	-
KQ224_RS07630 (KQ224_07630)	comGE	1459358..1459651 (+)	294	WP_105126461.1	competence type IV pilus minor pilin ComGE	-
KQ224_RS07635 (KQ224_07635)	comYF	1459638..1460072 (+)	435	WP_216806339.1	competence type IV pilus minor pilin ComGF	Machinery gene
KQ224_RS07640 (KQ224_07640)	comGG	1460050..1460550 (+)	501	WP_216806340.1	competence type IV pilus minor pilin ComGG	-
KQ224_RS07645 (KQ224_07645)	comYH	1460570..1461523 (+)	954	WP_024392669.1	class I SAM-dependent methyltransferase	Machinery gene
KQ224_RS07650 (KQ224_07650)	-	1461573..1462760 (+)	1188	WP_216806341.1	acetate kinase	-
KQ224_RS07655 (KQ224_07655)	-	1463015..1463566 (+)	552	WP_216806342.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 39272.27 Da
• Isoelectric Point: 9.4587

>NTDB_id=577595 KQ224_RS07615 WP_216806336.1 1457675..1458712(+) (comYB) [Streptococcus parasuis strain H35]
MSKLNAFLQRDISVLGRQKQKKLSLVRQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADQYTQVLSDGLLAGKPFSSLL
GDLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLAFLLLIMLGLKNYLLPQLEEGNVATI
LIQHLPTIFLSFCGLFFLAVLGGLIWYRRTNKIKAFSRLVALPFFGKLIQTYLTAYYAREWGSLIGQGLDMPQIVGLMQE
QKSQLFREIGEDLERSLSDGHSFHAHIQTYGFFKRELSLMIEYGQVKSKLGSELSVYATECWEEFFTRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide

• Length: 1038 bp

>NTDB_id=577595 KQ224_RS07615 WP_216806336.1 1457675..1458712(+) (comYB) [Streptococcus parasuis strain H35]
ATGAGCAAATTGAATGCCTTCTTGCAGCGGGACATATCAGTCCTCGGCAGGCAGAAACAGAAAAAATTGTCCTTGGTTCG
ACAGCGTAAGGTGATTGAGCTCTTTAACAATCTTTTTGCTAGTGGATTTCACTTGGGTGAAATTGTCGATTTTCTCAAAC
GGAGTCAACTCTTGGCTGACCAATACACGCAAGTTTTGTCCGACGGTCTTCTTGCAGGAAAGCCATTTTCAAGTCTTTTG
GGAGATTTACGCTTTTCGGATGCGGTTGTCACTCAGGTGGCCTTGGCGGAGGTTCATGGCAATACCAGTCTGAGTCTAAG
TCATATTCAATCTTATCTTGAAAATGTTAGCAAGGTGCGTAAAAAATTGATAGAAGTAGCAACCTATCCAATCATCTTGC
TTGCCTTTTTATTATTGATAATGTTGGGACTAAAAAACTATTTGTTGCCCCAGTTGGAAGAAGGAAATGTTGCGACTATA
TTGATTCAACACTTGCCAACAATCTTTTTATCCTTTTGTGGCCTTTTCTTTCTTGCTGTCTTAGGTGGGCTTATTTGGTA
TCGCAGAACAAATAAAATCAAGGCTTTTTCTCGCTTAGTAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATTTGA
CCGCCTATTACGCGAGGGAGTGGGGAAGCTTGATTGGTCAGGGACTTGATATGCCTCAGATTGTGGGCTTGATGCAGGAA
CAAAAATCACAGCTTTTTCGTGAGATTGGTGAAGATTTAGAGCGTTCGCTTTCTGATGGGCATAGTTTCCATGCTCATAT
CCAAACGTATGGCTTTTTCAAACGGGAGCTGAGTCTAATGATTGAGTATGGGCAAGTCAAATCAAAATTAGGAAGTGAGC
TATCTGTGTATGCAACAGAGTGTTGGGAGGAATTTTTTACTCGTGTTAATAGGGCCATGCAGTTGATTCAACCATTGGTT
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTATGCAGCCATGTTGCTGCCAATTTATCAGAATATGGAGTTATAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (33-150)

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus gordonii str. Challis substr. CH1	60.588	98.551	0.597
comYB	Streptococcus mutans UA140	60	98.551	0.591
comYB	Streptococcus mutans UA159	60	98.551	0.591
comGB/cglB	Streptococcus mitis SK321	60	97.101	0.583
comGB/cglB	Streptococcus mitis NCTC 12261	59.701	97.101	0.58
comGB/cglB	Streptococcus pneumoniae Rx1	59.104	97.101	0.574
comGB/cglB	Streptococcus pneumoniae D39	59.104	97.101	0.574
comGB/cglB	Streptococcus pneumoniae R6	59.104	97.101	0.574
comGB/cglB	Streptococcus pneumoniae TIGR4	59.104	97.101	0.574
comGB	Lactococcus lactis subsp. cremoris KW2	51.335	97.681	0.501