Detailed information NTG0056988

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: ATE38_RS06035
• Genome accession: NZ_AP017377
• Coordinates: 1195505..1195816 (+)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: A0A0H2XGS7
• Organism: Staphylococcus aureus strain OC8
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1190505..1200816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATE38_RS06010	-	1191142..1191471 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ATE38_RS06015	-	1191468..1192091 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ATE38_RS06020	comGA	1192143..1193117 (+)	975	WP_000697228.1	competence type IV pilus ATPase ComGA	Machinery gene
ATE38_RS06025	comGB	1193089..1194117 (+)	1029	WP_053015094.1	competence type IV pilus assembly protein ComGB	Machinery gene
ATE38_RS06030	-	1194203..1195375 (+)	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
ATE38_RS06035	comGC	1195505..1195816 (+)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
ATE38_RS06040	comGD	1195794..1196240 (+)	447	WP_001790850.1	competence type IV pilus minor pilin ComGD	Machinery gene
ATE38_RS06045	comGE	1196227..1196526 (+)	300	WP_000844413.1	hypothetical protein	Machinery gene
ATE38_RS06050	comGF	1196444..1196941 (+)	498	WP_001789864.1	competence type IV pilus minor pilin ComGF	Machinery gene
ATE38_RS06055	-	1197038..1197184 (+)	147	WP_001789879.1	hypothetical protein	-
ATE38_RS06060	-	1197174..1197698 (+)	525	WP_001015117.1	shikimate kinase	-
ATE38_RS06065	gcvT	1197857..1198948 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
ATE38_RS06070	gcvPA	1198968..1200314 (+)	1347	WP_000019687.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=56988 ATE38_RS06035 WP_000472256.1 1195505..1195816(+) (comGC) [Staphylococcus aureus strain OC8]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=56988 ATE38_RS06035 WP_000472256.1 1195505..1195816(+) (comGC) [Staphylococcus aureus strain OC8]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

3D structure

• AlphaFold DB: A0A0H2XGS7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comGC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comGC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369