Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KC397_RS00175 Genome accession   NZ_CP073273
Coordinates   38166..39281 (+) Length   371 a.a.
NCBI ID   WP_020332566.1    Uniprot ID   S7J652
Organism   Vibrio fluvialis strain 19-VB00936     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 33166..44281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KC397_RS00155 (KC397_00155) rsmB 34099..35379 (-) 1281 WP_208563689.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KC397_RS00160 (KC397_00160) fmt 35430..36377 (-) 948 WP_212570982.1 methionyl-tRNA formyltransferase -
  KC397_RS00165 (KC397_00165) def 36396..36908 (-) 513 WP_020332568.1 peptide deformylase -
  KC397_RS00170 (KC397_00170) - 37048..38166 (+) 1119 WP_212570984.1 LysM peptidoglycan-binding domain-containing protein -
  KC397_RS00175 (KC397_00175) dprA 38166..39281 (+) 1116 WP_020332566.1 DNA-processing protein DprA Machinery gene
  KC397_RS00180 (KC397_00180) - 39284..39760 (+) 477 WP_020332565.1 DUF494 family protein -
  KC397_RS00185 (KC397_00185) - 39791..40378 (+) 588 WP_024374494.1 type I DNA topoisomerase -
  KC397_RS00190 (KC397_00190) - 40412..41545 (-) 1134 WP_212570986.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  KC397_RS00195 (KC397_00195) purE 41549..42034 (-) 486 WP_212570989.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  KC397_RS00200 (KC397_00200) - 42233..42790 (+) 558 WP_212570991.1 L-threonylcarbamoyladenylate synthase -
  KC397_RS00205 (KC397_00205) hemF 42810..43724 (+) 915 WP_212570993.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 371 a.a.        Molecular weight: 40529.98 Da        Isoelectric Point: 6.2298

>NTDB_id=558702 KC397_RS00175 WP_020332566.1 38166..39281(+) (dprA) [Vibrio fluvialis strain 19-VB00936]
MLERDLAAWLAFSFTPQLGIRTLQRLASRYALSDLKQHLNRDGLAVGLKDNQIQYLQRQADQDVDACLRWSDQADNRHIL
TPFHAHYPSLLTEIAAAPPVLFVEGRLEALRAPQIAIVGSRNASIDSQQIAHQFATQLVEHGLVVTSGLALGIDGYAHDG
ALKAGGETIAVLGSGLECIYPARHRALAGRIVDRGALVSEFRPDAKPRPDHFPRRNRIISGLSLGVLVVEAAEKSGSLIT
ARYAAEQSREVFVVPGSIRNPNSLGSNQLIRQGACLVQHVDHILEEVSSLMDWSRNQSQPEQTELFSGTYNEEELPFPEL
LANVGGEATPVDILANRTNIPVQDVMMQLLELELSGHVVAVSGGYIRKGRG

Nucleotide


Download         Length: 1116 bp        

>NTDB_id=558702 KC397_RS00175 WP_020332566.1 38166..39281(+) (dprA) [Vibrio fluvialis strain 19-VB00936]
ATGCTCGAACGCGATCTGGCTGCTTGGCTGGCTTTCAGTTTTACTCCTCAACTCGGTATCCGAACACTGCAGCGTTTAGC
TAGTCGTTACGCGCTGTCTGACCTCAAACAACACCTGAATCGTGACGGCTTGGCCGTAGGGCTGAAAGACAACCAGATTC
AGTATTTGCAGCGGCAGGCCGATCAAGACGTCGATGCCTGCCTGCGTTGGAGTGATCAGGCTGATAACCGCCATATTCTG
ACGCCGTTTCATGCGCACTATCCCTCGTTATTGACCGAAATCGCCGCCGCTCCGCCAGTGCTGTTTGTGGAGGGGCGGCT
TGAAGCGCTGCGTGCGCCGCAAATTGCTATTGTCGGCAGTCGCAACGCCAGTATCGACAGTCAGCAAATCGCTCATCAAT
TTGCCACGCAATTGGTCGAACACGGTTTGGTGGTCACCAGTGGTCTGGCGCTTGGTATTGATGGCTACGCGCATGATGGA
GCACTCAAAGCGGGTGGGGAAACTATTGCGGTGCTGGGCTCGGGGCTGGAATGTATTTATCCGGCTCGCCATCGCGCGTT
GGCGGGGCGTATTGTTGACAGAGGCGCCTTGGTGTCGGAATTTCGCCCTGATGCCAAGCCTCGACCTGATCATTTTCCGC
GTCGTAATCGTATTATCAGTGGGTTGTCATTGGGCGTTCTGGTGGTGGAAGCGGCGGAAAAAAGTGGCTCGCTCATCACC
GCGCGTTATGCCGCCGAACAGAGCCGAGAGGTGTTTGTCGTGCCGGGCTCAATTCGCAACCCGAATAGCCTCGGCAGTAA
CCAGTTGATTCGACAAGGGGCGTGTTTGGTACAACATGTCGATCATATTCTCGAAGAAGTCAGCAGTTTGATGGACTGGA
GCCGAAATCAGTCACAACCTGAGCAGACAGAACTTTTTTCTGGCACATATAACGAAGAAGAATTGCCATTTCCCGAGCTG
TTAGCTAACGTAGGGGGAGAGGCTACACCAGTTGATATTCTTGCAAACAGGACCAATATACCTGTCCAGGATGTCATGAT
GCAGCTCCTGGAGCTTGAGCTTTCAGGGCATGTTGTTGCAGTTTCCGGTGGCTATATTCGTAAGGGGAGGGGCTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(76-278)

DprA winged helix domain (DprA_WH)

(319-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S7J652

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae strain A1552

64.69

100

0.647
  dprA Vibrio campbellii strain DS40M4

64.85

98.922

0.642
  dprA Glaesserella parasuis strain SC1401

45.699

100

0.458
  dprA Legionella pneumophila strain ERS1305867

43.407

98.113

0.426
  dprA Neisseria meningitidis MC58

37.437

100

0.402
  dprA Neisseria meningitidis strain C311

37.437

100

0.402
  dprA Haemophilus influenzae Rd KW20

44.012

90.027

0.396
  dprA Acinetobacter baumannii strain A118

42.229

91.914

0.388
  dprA Neisseria gonorrhoeae MS11

35.93

100

0.385
  dprA Acinetobacter baumannii D1279779

42.183

91.375

0.385
  dprA Neisseria gonorrhoeae strain FA1090

35.443

100

0.377
  dprA Acinetobacter baylyi ADP1

41.916

90.027

0.377