Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   J7U24_RS02960 Genome accession   NZ_CP072440
Coordinates   562484..563710 (+) Length   408 a.a.
NCBI ID   WP_372434727.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24730     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 557484..568710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U24_RS02935 (J7U24_02930) - 558059..559330 (-) 1272 WP_084829446.1 hydroxymethylglutaryl-CoA reductase, degradative -
  J7U24_RS02940 (J7U24_02935) - 559323..560498 (-) 1176 WP_220016575.1 hydroxymethylglutaryl-CoA synthase -
  J7U24_RS02945 (J7U24_02940) - 560820..561680 (+) 861 WP_002950145.1 thymidylate synthase -
  J7U24_RS02950 (J7U24_02945) - 561788..562291 (+) 504 WP_116920143.1 dihydrofolate reductase -
  J7U24_RS02955 (J7U24_02950) - 562296..562466 (+) 171 WP_002886174.1 hypothetical protein -
  J7U24_RS02960 (J7U24_02955) clpX 562484..563710 (+) 1227 WP_372434727.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  J7U24_RS02965 (J7U24_02960) yihA 563720..564319 (+) 600 WP_206285241.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  J7U24_RS02970 (J7U24_02965) - 564449..565825 (+) 1377 WP_372434728.1 amino acid permease -
  J7U24_RS02975 (J7U24_02970) mmuM 565837..566787 (+) 951 WP_084831028.1 homocysteine S-methyltransferase -
  J7U24_RS02980 (J7U24_02975) - 566900..567154 (+) 255 WP_002950164.1 DUF1912 family protein -
  J7U24_RS02985 (J7U24_02980) - 567226..567585 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  J7U24_RS02990 (J7U24_02985) plsY 567699..568340 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45048.44 Da        Isoelectric Point: 4.4119

>NTDB_id=553214 J7U24_RS02960 WP_372434727.1 562484..563710(+) (clpX) [Streptococcus thermophilus strain S24730]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=553214 J7U24_RS02960 WP_372434727.1 562484..563710(+) (clpX) [Streptococcus thermophilus strain S24730]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATTCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCAGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.998

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566