NTDB

Overview

Name	comGC/cglC	Type	Machinery gene
Locus tag	JZI48_RS04265	Genome accession	NZ_CP071145
Coordinates	902152..902475 (-)	Length	107 a.a.
NCBI ID	WP_012514782.1	Uniprot ID	B4U056
Organism	Streptococcus equi subsp. equi strain 470_007
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 897152..907475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZI48_RS04235 (JZI48_04235)	comYH	898295..899248 (-)	954	WP_012678816.1	class I SAM-dependent methyltransferase	Machinery gene
JZI48_RS04240 (JZI48_04240)	-	899333..900675 (-)	1343	Protein_852	IS3 family transposase	-
JZI48_RS04245 (JZI48_04245)	comGG	900741..901103 (-)	363	WP_012678815.1	competence type IV pilus minor pilin ComGG	-
JZI48_RS04250 (JZI48_04250)	comYF	901081..901515 (-)	435	WP_012678814.1	competence type IV pilus minor pilin ComGF	Machinery gene
JZI48_RS04255 (JZI48_04255)	comGE	901502..901792 (-)	291	WP_012678813.1	competence type IV pilus minor pilin ComGE	-
JZI48_RS04260 (JZI48_04260)	comGD	901749..902174 (-)	426	WP_012678812.1	competence type IV pilus minor pilin ComGD	-
JZI48_RS04265 (JZI48_04265)	comGC/cglC	902152..902475 (-)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
JZI48_RS04270 (JZI48_04270)	comYB	902476..903510 (-)	1035	WP_012678811.1	competence type IV pilus assembly protein ComGB	Machinery gene
JZI48_RS04275 (JZI48_04275)	comGA/cglA	903443..904381 (-)	939	WP_012678810.1	competence type IV pilus ATPase ComGA	Machinery gene
JZI48_RS04280 (JZI48_04280)	-	904563..905210 (-)	648	WP_012678809.1	ATP-binding cassette domain-containing protein	-
JZI48_RS04285 (JZI48_04285)	-	905212..907215 (-)	2004	WP_012678808.1	DUF1430 domain-containing protein	-

Sequence

Protein

Download Length: 107 a.a. Molecular weight: 12149.19 Da Isoelectric Point: 8.4057

                                >NTDB_id=543166 JZI48_RS04265 WP_012514782.1 902152..902475(-) (comGC/cglC) [Streptococcus equi subsp. equi strain 470_007]

MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE

DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

Download Length: 324 bp

                                >NTDB_id=543166 JZI48_RS04265 WP_012514782.1 902152..902475(-) (comGC/cglC) [Streptococcus equi subsp. equi strain 470_007]

ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT

CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG

TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG

GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA

TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	B4U056

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364

Detailed information NTG0543166