NTDB

Overview

Name	comGC/cglC	Type	Machinery gene
Locus tag	JZI59_RS06615	Genome accession	NZ_CP071144
Coordinates	1362552..1362875 (+)	Length	107 a.a.
NCBI ID	WP_012514782.1	Uniprot ID	B4U056
Organism	Streptococcus equi subsp. equi strain 470_008
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1357552..1367875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZI59_RS06595 (JZI59_06595)	-	1357812..1359815 (+)	2004	WP_012678808.1	DUF1430 domain-containing protein	-
JZI59_RS06600 (JZI59_06600)	-	1359817..1360464 (+)	648	WP_012678809.1	ATP-binding cassette domain-containing protein	-
JZI59_RS06605 (JZI59_06605)	comGA/cglA	1360646..1361584 (+)	939	WP_012678810.1	competence type IV pilus ATPase ComGA	Machinery gene
JZI59_RS06610 (JZI59_06610)	comYB	1361517..1362551 (+)	1035	WP_012678811.1	competence type IV pilus assembly protein ComGB	Machinery gene
JZI59_RS06615 (JZI59_06615)	comGC/cglC	1362552..1362875 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
JZI59_RS06620 (JZI59_06620)	comGD	1362853..1363278 (+)	426	WP_012678812.1	competence type IV pilus minor pilin ComGD	-
JZI59_RS06625 (JZI59_06625)	comGE	1363235..1363525 (+)	291	WP_012678813.1	competence type IV pilus minor pilin ComGE	-
JZI59_RS06630 (JZI59_06630)	comYF	1363512..1363946 (+)	435	WP_012678814.1	competence type IV pilus minor pilin ComGF	Machinery gene
JZI59_RS06635 (JZI59_06635)	comGG	1363924..1364286 (+)	363	WP_012678815.1	competence type IV pilus minor pilin ComGG	-
JZI59_RS06640 (JZI59_06640)	-	1364352..1365694 (+)	1343	Protein_1255	IS3 family transposase	-
JZI59_RS06645 (JZI59_06645)	comYH	1365779..1366732 (+)	954	WP_012678816.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

Download Length: 107 a.a. Molecular weight: 12149.19 Da Isoelectric Point: 8.4057

                                >NTDB_id=543122 JZI59_RS06615 WP_012514782.1 1362552..1362875(+) (comGC/cglC) [Streptococcus equi subsp. equi strain 470_008]

MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE

DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

Download Length: 324 bp

                                >NTDB_id=543122 JZI59_RS06615 WP_012514782.1 1362552..1362875(+) (comGC/cglC) [Streptococcus equi subsp. equi strain 470_008]

ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT

CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG

TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG

GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA

TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	B4U056

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364

Detailed information NTG0543122