Detailed information NTG0543121

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: JZI59_RS06610
• Genome accession: NZ_CP071144
• Coordinates: 1361517..1362551 (+)
• Length: 344 a.a.
• NCBI ID: WP_012678811.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. equi strain 470_008
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1356517..1367551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZI59_RS06590 (JZI59_06590)	-	1356910..1357275 (+)	366	WP_012514777.1	DUF1033 family protein	-
JZI59_RS06595 (JZI59_06595)	-	1357812..1359815 (+)	2004	WP_012678808.1	DUF1430 domain-containing protein	-
JZI59_RS06600 (JZI59_06600)	-	1359817..1360464 (+)	648	WP_012678809.1	ATP-binding cassette domain-containing protein	-
JZI59_RS06605 (JZI59_06605)	comGA/cglA	1360646..1361584 (+)	939	WP_012678810.1	competence type IV pilus ATPase ComGA	Machinery gene
JZI59_RS06610 (JZI59_06610)	comYB	1361517..1362551 (+)	1035	WP_012678811.1	competence type IV pilus assembly protein ComGB	Machinery gene
JZI59_RS06615 (JZI59_06615)	comGC/cglC	1362552..1362875 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
JZI59_RS06620 (JZI59_06620)	comGD	1362853..1363278 (+)	426	WP_012678812.1	competence type IV pilus minor pilin ComGD	-
JZI59_RS06625 (JZI59_06625)	comGE	1363235..1363525 (+)	291	WP_012678813.1	competence type IV pilus minor pilin ComGE	-
JZI59_RS06630 (JZI59_06630)	comYF	1363512..1363946 (+)	435	WP_012678814.1	competence type IV pilus minor pilin ComGF	Machinery gene
JZI59_RS06635 (JZI59_06635)	comGG	1363924..1364286 (+)	363	WP_012678815.1	competence type IV pilus minor pilin ComGG	-
JZI59_RS06640 (JZI59_06640)	-	1364352..1365694 (+)	1343	Protein_1255	IS3 family transposase	-
JZI59_RS06645 (JZI59_06645)	comYH	1365779..1366732 (+)	954	WP_012678816.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 344 a.a.
• Molecular weight: 39431.69 Da
• Isoelectric Point: 9.4359

>NTDB_id=543121 JZI59_RS06610 WP_012678811.1 1361517..1362551(+) (comYB) [Streptococcus equi subsp. equi strain 470_008]
MISFLRRDISIPGRQGLKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYVTSMEASLLKGNGLADMLAAL
GYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKRKTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLL
HLPHYFLGFCLLVLLLIGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEMMSNEKS
QLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELDIYSQESWETFFSQLNRATQWIQPIIFLV
VAVVIVMIYAAILLPIYQQMGDVF

Nucleotide

• Length: 1035 bp

>NTDB_id=543121 JZI59_RS06610 WP_012678811.1 1361517..1362551(+) (comYB) [Streptococcus equi subsp. equi strain 470_008]
TTGATCAGCTTCTTGCGGAGGGACATCTCAATACCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAAGCAGCAGGAAAA
GCTTATCCAATTGCTCTATAACCTATTGTCTAACGGCTTTAATTTGACAGAGGTCATTGCTTTTTTGAGAAAAAGCCAGC
TGCTACTGCCAGTCTATGTTACAAGTATGGAAGCAAGCCTATTAAAGGGCAACGGCCTTGCTGACATGCTAGCAGCCTTA
GGTTACTCTGATGCTGTTATGACACAAATTAATCTGGCAGATAAGCATGGCAATATCAAGCTAACCTTGGAAAAAATTCA
GGACTATCTGAGTCAATTTCGCCAAATCAAGCGAAAGACCATCGAGGCAGTCACTTATCCGATTATACTTTTGGGTTTTC
TAGTGGTTATCATGCTAGGCTTGCGTCATTACCTAATCCCTCAGCTAGAGAGTCAAAATACCTTGACTGACTTGTTGCTT
CATTTGCCTCATTATTTCTTAGGTTTTTGTTTGCTTGTGCTGTTGCTAATTGGCTCTTTTTACCTATATGCCAAGTCCTG
TAGTCGGCTAAAACTATTTAGTCAGCTGAGCTATTATCCTATCATTGGGTCCTTATTGCGGCAATATTTGACAGCCTACT
ATGCTAGAGAATGGGGCAACCTCATCGGACAAGGCTTAGAATTAATCACCATTTTAGAGATGATGTCAAACGAAAAGTCA
CAGCTCATGCGAGAGCTTGCCAAGGATATCAAGCAGAGTCTACTAGCTGGCCAATCCTTTCATCAAAGGGTTGCAGCTTA
TCCCTTTTTTAAAAAGGAGCTAAGCCTAATGATTGAATATGGTGACATCAAATCAAAGCTTGGTCAGGAATTAGATATCT
ATTCCCAAGAAAGCTGGGAGACCTTTTTTAGTCAGCTTAATCGGGCAACACAATGGATCCAGCCGATTATTTTTTTAGTG
GTTGCTGTGGTTATTGTGATGATTTATGCTGCTATTTTATTACCAATTTATCAACAGATGGGAGATGTTTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (215-335)

• Type II secretion system (T2SS), protein F (T2SSF) (29-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	53.982	98.547	0.532
comYB	Streptococcus mutans UA159	53.982	98.547	0.532
comYB	Streptococcus gordonii str. Challis substr. CH1	52.059	98.837	0.515
comGB/cglB	Streptococcus mitis NCTC 12261	48.81	97.674	0.477
comGB/cglB	Streptococcus mitis SK321	49.249	96.802	0.477
comGB/cglB	Streptococcus pneumoniae Rx1	48.649	96.802	0.471
comGB/cglB	Streptococcus pneumoniae D39	48.649	96.802	0.471
comGB/cglB	Streptococcus pneumoniae R6	48.649	96.802	0.471
comGB/cglB	Streptococcus pneumoniae TIGR4	48.649	96.802	0.471
comGB	Lactococcus lactis subsp. cremoris KW2	46.933	94.767	0.445