Detailed information NTG0537277

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: I6K87_RS07530
• Genome accession: NZ_CP069892
• Coordinates: 1527731..1528480 (+)
• Length: 249 a.a.
• NCBI ID: WP_049517113.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1522731..1533480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS07500 (I6K87_07500)	spo0J	1523276..1524043 (-)	768	WP_059221676.1	ParB/RepB/Spo0J family partition protein	Regulator
I6K87_RS07505 (I6K87_07505)	htrA	1524098..1525288 (-)	1191	WP_003029517.1	S1C family serine protease	Regulator
I6K87_RS07510 (I6K87_07510)	rlmH	1525481..1525960 (+)	480	WP_049533214.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I6K87_RS07520 (I6K87_07520)	-	1526242..1526388 (+)	147	WP_003029519.1	bacteriocin	-
I6K87_RS07525 (I6K87_07525)	comD/comD2	1526409..1527731 (+)	1323	WP_218969867.1	sensor histidine kinase	Regulator
I6K87_RS07530 (I6K87_07530)	comE	1527731..1528480 (+)	750	WP_049517113.1	competence system response regulator transcription factor ComE	Regulator
I6K87_RS07545 (I6K87_07545)	-	1528828..1531404 (-)	2577	WP_003040707.1	YfhO family protein	-
I6K87_RS07550 (I6K87_07550)	-	1531471..1533093 (-)	1623	WP_204982519.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29202.85 Da
• Isoelectric Point: 8.6042

>NTDB_id=537277 I6K87_RS07530 WP_049517113.1 1527731..1528480(+) (comE) [Streptococcus anginosus strain FDAARGOS_1357]
MKVLVLEDEISHQVRMETTLAEIAKEMGITIKVKVTGKVREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLSDVAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETRRFFSPHKSYLVNIGNIKGYDKKMREIIFYEDHRCPITRMKIGKL
KAILEELKG

Nucleotide

• Length: 750 bp

>NTDB_id=537277 I6K87_RS07530 WP_049517113.1 1527731..1528480(+) (comE) [Streptococcus anginosus strain FDAARGOS_1357]
ATGAAAGTATTAGTATTAGAAGATGAAATTTCACATCAAGTAAGAATGGAAACAACTTTGGCAGAGATTGCGAAAGAAAT
GGGAATTACGATAAAAGTTAAAGTAACTGGCAAAGTAAGAGAATTTAAAGAATATATTGAAAATGATGAGGTGAATCAAT
TATATTTTTTAGATATTGATATCAAAGGAGAGGAAACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCACAATCCG
TATGCTATTATTGTTTTTGTTACAACGAAATCAGAATTTGCCACTATGACCTTCAAATATAAGGTATCTGCACTGGATTT
TGTTGATAAAAATTTGAGTGATGTTGCTTTTAAAAAACATATAAAAGACAGCATTGAGTATACAAAAGCGACATTGATTG
AAAATAAAGATATGGTGGATTATTTTGAATATAGCTTTCGTGGCGGAGAGGTTAGAATGCCTTTTAATGACATTTTATAT
ATTGAAACGACAGGTTCTTCTCATAAATTAAGAATTGTCGGTAAAAACTTTTTTAAAGAATTTTATGGTACTATTGCAGA
TATTCAAGAAAAAGATAAAGAAACAAGACGTTTCTTTTCACCTCATAAATCTTATCTAGTCAATATTGGAAACATCAAAG
GTTATGACAAAAAAATGCGAGAAATAATTTTTTATGAAGATCATCGTTGTCCGATTACTCGAATGAAAATTGGAAAGTTA
AAGGCTATTTTAGAGGAATTAAAAGGATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-121)

• LytTr DNA-binding domain (LytTR) (152-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	70.612	98.394	0.695
comE/comE2	Streptococcus gordonii strain NCTC7865	70.492	97.992	0.691
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	70.492	97.992	0.691
comE	Streptococcus infantis strain Atu-4	69.796	98.394	0.687
comE	Streptococcus mitis SK321	69.796	98.394	0.687
comE	Streptococcus pneumoniae Rx1	69.388	98.394	0.683
comE	Streptococcus pneumoniae D39	69.388	98.394	0.683
comE	Streptococcus pneumoniae R6	69.388	98.394	0.683
comE	Streptococcus pneumoniae TIGR4	69.388	98.394	0.683
comE/blpR	Streptococcus mutans UA159	40.486	99.197	0.402
comE/comE2	Streptococcus equinus JB1	34.749	100	0.361