Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   I6K87_RS07525 Genome accession   NZ_CP069892
Coordinates   1526409..1527731 (+) Length   440 a.a.
NCBI ID   WP_218969867.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1521409..1532731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS07495 (I6K87_07495) dnaA 1521705..1523048 (-) 1344 WP_003029515.1 chromosomal replication initiator protein DnaA -
  I6K87_RS07500 (I6K87_07500) spo0J 1523276..1524043 (-) 768 WP_059221676.1 ParB/RepB/Spo0J family partition protein Regulator
  I6K87_RS07505 (I6K87_07505) htrA 1524098..1525288 (-) 1191 WP_003029517.1 S1C family serine protease Regulator
  I6K87_RS07510 (I6K87_07510) rlmH 1525481..1525960 (+) 480 WP_049533214.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6K87_RS07520 (I6K87_07520) - 1526242..1526388 (+) 147 WP_003029519.1 bacteriocin -
  I6K87_RS07525 (I6K87_07525) comD/comD2 1526409..1527731 (+) 1323 WP_218969867.1 sensor histidine kinase Regulator
  I6K87_RS07530 (I6K87_07530) comE 1527731..1528480 (+) 750 WP_049517113.1 competence system response regulator transcription factor ComE Regulator
  I6K87_RS07545 (I6K87_07545) - 1528828..1531404 (-) 2577 WP_003040707.1 YfhO family protein -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51962.71 Da        Isoelectric Point: 8.9107

>NTDB_id=537276 I6K87_RS07525 WP_218969867.1 1526409..1527731(+) (comD/comD2) [Streptococcus anginosus strain FDAARGOS_1357]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKVK
KHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKADFKENIVQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVNLYN
EIRGFRHDYGGMLASFQSAIHTGNIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=537276 I6K87_RS07525 WP_218969867.1 1526409..1527731(+) (comD/comD2) [Streptococcus anginosus strain FDAARGOS_1357]
GTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATACTGCTATAAGAAAATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTTAACTGATTTCACTACTTTAATAC
ATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAAA
AAACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATCATTTCTTTAGTTTTTA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTTAAAGAGAATATTGTGCAGTTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTGTCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAGAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATTGTTAATCTGTATAAT
GAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTAATATAAAAGA
AGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTCAAGCCCCTGCCGATTAAATTGTTAGATCTGGTTAGAATGACAAGCGTCCTTTTGAATAA
TGCCATAGAAGGATCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAG
TCATTCAAAATTCACGTAAGAAAAGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.543
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.338

99.545

0.541
  comD Streptococcus mitis SK321

47.704

89.091

0.425
  comD Streptococcus mitis NCTC 12261

48.936

85.455

0.418
  comD/comD2 Streptococcus pneumoniae TIGR4

48.67

85.455

0.416
  comD/comD1 Streptococcus pneumoniae Rx1

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae D39

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae R6

48.138

85.455

0.411