Detailed information NTG0534547

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: JQM34_RS06885
• Genome accession: NZ_CP069427
• Coordinates: 1441441..1442193 (+)
• Length: 250 a.a.
• NCBI ID: WP_200370611.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SF100
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1436441..1447193

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQM34_RS06855 (JQM34_0001398)	spo0J	1437020..1437778 (-)	759	WP_200370607.1	ParB/RepB/Spo0J family partition protein	Regulator
JQM34_RS06860 (JQM34_0001399)	htrA	1437836..1439032 (-)	1197	WP_000681800.1	S1C family serine protease	Regulator
JQM34_RS06865 (JQM34_0001400)	rlmH	1439218..1439697 (+)	480	WP_200370609.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
JQM34_RS06875 (JQM34_0001402)	comC/comC2	1439979..1440104 (+)	126	WP_000799678.1	competence-stimulating peptide ComC	Regulator
JQM34_RS06880 (JQM34_0001403)	comD	1440125..1441444 (+)	1320	WP_000362886.1	competence system sensor histidine kinase ComD	Regulator
JQM34_RS06885 (JQM34_0001404)	comE	1441441..1442193 (+)	753	WP_200370611.1	competence system response regulator transcription factor ComE	Regulator
JQM34_RS06900 (JQM34_0001407)	-	1442431..1442973 (-)	543	WP_000665080.1	TetR-like C-terminal domain-containing protein	-
JQM34_RS06905 (JQM34_0001408)	-	1443101..1445755 (+)	2655	WP_000472066.1	YhgE/Pip domain-containing protein	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29912.29 Da
• Isoelectric Point: 6.9755

>NTDB_id=534547 JQM34_RS06885 WP_200370611.1 1441441..1442193(+) (comE) [Streptococcus oralis strain SF100]
MKVLILEDVIEHQVRLERILNEISEESNIPISYKTTGKVREFKEYIENDEVNQLYFLDIDIHGIEKKGFEVAQFIRHHNP
YVIIVFITSRSEFATLTYKYQVSALDFVDKDINDELFKKRIEQSIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYCSHKSFLVNVGNVREIDRKNLEVVFYEDHRCPITRLKVRKL
KDILEKKSKK

Nucleotide

• Length: 753 bp

>NTDB_id=534547 JQM34_RS06885 WP_200370611.1 1441441..1442193(+) (comE) [Streptococcus oralis strain SF100]
ATGAAAGTATTAATTTTAGAAGATGTTATTGAACATCAAGTGAGACTAGAGAGAATATTAAATGAAATCTCGGAAGAATC
GAATATTCCTATTTCATATAAGACAACAGGAAAAGTTCGTGAGTTTAAGGAATATATCGAAAATGATGAAGTAAACCAGC
TTTATTTCCTAGATATCGATATTCATGGAATCGAGAAAAAAGGCTTTGAAGTGGCTCAGTTTATCCGTCATCACAATCCT
TATGTTATTATTGTCTTTATTACCAGTCGATCTGAATTTGCTACCTTAACTTACAAATACCAGGTATCAGCTCTAGATTT
TGTAGACAAAGACATCAATGATGAATTGTTCAAAAAACGTATCGAGCAGAGTATTTTTTACACTAAGAGTATGCTGCTTG
AAAACGAAGATGTTGTAGACTATTTTGATTACAACTATAAGGGAAATGATTTGAAAATTCCTTACCATGACATTTTGTAT
ATCGAAACCACAGGAGTTTCTCATAAACTTCGGATTATTGGTAAGAATTTTGCTAAAGAATTCTATGGAACTATGACAGA
TATTCAGGAAAAGGACAAACATACCCAGCGATTTTATTGCTCCCATAAATCTTTCCTTGTCAATGTGGGAAATGTGAGAG
AAATTGATCGAAAGAATTTAGAAGTTGTCTTTTATGAAGATCATCGTTGCCCGATTACCCGTTTGAAAGTTCGCAAACTA
AAAGATATTCTAGAGAAAAAATCTAAAAAGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-244)

• Response regulator receiver domain (Response_reg) (3-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	95.2	100	0.952
comE	Streptococcus mitis SK321	94.4	100	0.944
comE	Streptococcus pneumoniae Rx1	93.6	100	0.936
comE	Streptococcus pneumoniae D39	93.6	100	0.936
comE	Streptococcus pneumoniae R6	93.6	100	0.936
comE	Streptococcus pneumoniae TIGR4	93.6	100	0.936
comE	Streptococcus infantis strain Atu-4	93.2	100	0.932
comE/comE2	Streptococcus gordonii strain NCTC7865	62.8	100	0.628
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	62.8	100	0.628
comE/blpR	Streptococcus mutans UA159	40.081	98.8	0.396