Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   JQM34_RS06880 Genome accession   NZ_CP069427
Coordinates   1440125..1441444 (+) Length   439 a.a.
NCBI ID   WP_000362886.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1435125..1446444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQM34_RS06850 (JQM34_0001397) dnaA 1435442..1436803 (-) 1362 WP_000660625.1 chromosomal replication initiator protein DnaA -
  JQM34_RS06855 (JQM34_0001398) spo0J 1437020..1437778 (-) 759 WP_200370607.1 ParB/RepB/Spo0J family partition protein Regulator
  JQM34_RS06860 (JQM34_0001399) htrA 1437836..1439032 (-) 1197 WP_000681800.1 S1C family serine protease Regulator
  JQM34_RS06865 (JQM34_0001400) rlmH 1439218..1439697 (+) 480 WP_200370609.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  JQM34_RS06875 (JQM34_0001402) comC/comC2 1439979..1440104 (+) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  JQM34_RS06880 (JQM34_0001403) comD 1440125..1441444 (+) 1320 WP_000362886.1 competence system sensor histidine kinase ComD Regulator
  JQM34_RS06885 (JQM34_0001404) comE 1441441..1442193 (+) 753 WP_200370611.1 competence system response regulator transcription factor ComE Regulator
  JQM34_RS06900 (JQM34_0001407) - 1442431..1442973 (-) 543 WP_000665080.1 TetR-like C-terminal domain-containing protein -
  JQM34_RS06905 (JQM34_0001408) - 1443101..1445755 (+) 2655 WP_000472066.1 YhgE/Pip domain-containing protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51241.29 Da        Isoelectric Point: 7.0077

>NTDB_id=534546 JQM34_RS06880 WP_000362886.1 1440125..1441444(+) (comD) [Streptococcus oralis strain SF100]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFCYTCISVFILEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKAIFISLLLSLLYHSTHTFISVTLSSIIGDEVVLHYKSTFLLVVLLMTYFSILIIIRYFHLDIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKVQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=534546 JQM34_RS06880 WP_000362886.1 1440125..1441444(+) (comD) [Streptococcus oralis strain SF100]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAAGCTATTTTTATCAGTTTACTACTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACCTTATCTTC
TATAATAGGAGATGAAGTAGTATTACACTATAAAAGTACATTCCTTTTAGTAGTATTGTTAATGACTTATTTTTCTATTC
TAATAATAATCCGTTATTTTCATCTGGATATTAAATATTTTGATAAAGATTATCTGTACCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTACATATCTTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCACAAGGTTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGGATGCTTGTTAGCATGCAAATGGCGATTGACAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCTTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTACTTTGATTTAAATA
ATATAGAAGACTCTGCTTTACGAAGTTTAATTGCTCAATCGATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAACAATGC
TGTTGAAGGTGCTGCAGATAGTTATTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATCACTATGACGCCTTCAGAGGATTTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAAGGAGATTTTAGATAAGTATGACAACATTATTTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

75.057

100

0.754
  comD Streptococcus mitis NCTC 12261

74.603

100

0.749
  comD/comD2 Streptococcus pneumoniae TIGR4

74.15

100

0.745
  comD/comD1 Streptococcus pneumoniae R6

73.696

100

0.74
  comD/comD1 Streptococcus pneumoniae Rx1

73.696

100

0.74
  comD/comD1 Streptococcus pneumoniae D39

73.696

100

0.74
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.465

85.194

0.421
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.936

85.649

0.419