Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   JO410_RS08640 Genome accession   NZ_CP069185
Coordinates   1762201..1762476 (-) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain L11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1757201..1767476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JO410_RS08595 (JO410_08595) - 1757237..1757419 (+) 183 WP_002364224.1 YegP family protein -
  JO410_RS08600 (JO410_08600) - 1757459..1758184 (-) 726 WP_174092948.1 Rha family transcriptional regulator -
  JO410_RS08605 (JO410_08605) - 1758223..1758534 (-) 312 WP_002381719.1 hypothetical protein -
  JO410_RS08610 (JO410_08610) - 1758545..1758721 (-) 177 WP_002364354.1 helix-turn-helix domain-containing protein -
  JO410_RS08615 (JO410_08615) - 1759033..1759365 (+) 333 WP_002364355.1 helix-turn-helix domain-containing protein -
  JO410_RS08620 (JO410_08620) - 1759382..1759726 (+) 345 WP_002395798.1 ImmA/IrrE family metallo-endopeptidase -
  JO410_RS08625 (JO410_08625) - 1759760..1760488 (+) 729 WP_002364358.1 ion transporter -
  JO410_RS08630 (JO410_08630) - 1760585..1761733 (+) 1149 WP_002364359.1 tyrosine-type recombinase/integrase -
  JO410_RS08635 (JO410_08635) comGD 1761761..1762204 (-) 444 WP_002384345.1 competence type IV pilus minor pilin ComGD -
  JO410_RS08640 (JO410_08640) comGC/cglC 1762201..1762476 (-) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  JO410_RS08645 (JO410_08645) comGB 1762476..1763522 (-) 1047 WP_002369171.1 competence type IV pilus assembly protein ComGB -
  JO410_RS08650 (JO410_08650) comGA 1763479..1764447 (-) 969 WP_002364362.1 competence type IV pilus ATPase ComGA -
  JO410_RS08655 (JO410_08655) - 1764688..1766016 (-) 1329 WP_002360022.1 APC family permease -
  JO410_RS08660 (JO410_08660) rlmN 1766306..1767379 (-) 1074 WP_002378471.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=532791 JO410_RS08640 WP_002356991.1 1762201..1762476(-) (comGC/cglC) [Enterococcus faecalis strain L11]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=532791 JO410_RS08640 WP_002356991.1 1762201..1762476(-) (comGC/cglC) [Enterococcus faecalis strain L11]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582

  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571

  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571

  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549

  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538

  comYC Streptococcus suis isolate S10

52.326

94.505

0.495

  comYC Streptococcus mutans UA159

57.692

85.714

0.495

  comYC Streptococcus mutans UA140

57.692

85.714

0.495

  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462

  comGC Staphylococcus aureus MW2

46.835

86.813

0.407

  comGC Staphylococcus aureus N315

46.835

86.813

0.407

  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396