Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilM   Type   Machinery gene
Locus tag   LPV_RS04920 Genome accession   NC_018140
Coordinates   1061209..1062273 (+) Length   354 a.a.
NCBI ID   WP_014843599.1    Uniprot ID   A0A4T1VG56
Organism   Legionella pneumophila subsp. pneumophila     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1056209..1067273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPV_RS04910 (LPV_1062) - 1057250..1059634 (-) 2385 WP_014843597.1 penicillin-binding protein 1A -
  LPV_RS04915 (LPV_1063) - 1059786..1060793 (-) 1008 WP_014843598.1 hypothetical protein -
  LPV_RS04920 (LPV_1064) pilM 1061209..1062273 (+) 1065 WP_014843599.1 type IV pilus assembly protein PilM Machinery gene
  LPV_RS04925 (LPV_1065) pilN 1062277..1062825 (+) 549 WP_011213354.1 PilN domain-containing protein Machinery gene
  LPV_RS04930 (LPV_1066) pilO 1062839..1063438 (+) 600 WP_014843600.1 type 4a pilus biogenesis protein PilO Machinery gene
  LPV_RS04935 (LPV_1067) pilP 1063435..1064019 (+) 585 WP_014843601.1 pilus assembly protein PilP Machinery gene
  LPV_RS04940 (LPV_1068) pilQ 1064023..1066119 (+) 2097 WP_014843602.1 type IV pilus secretin PilQ Machinery gene
  LPV_RS04945 (LPV_1069) aroK 1066565..1067092 (+) 528 WP_010946667.1 shikimate kinase AroK -

Sequence

Protein


Download         Length: 354 a.a.        Molecular weight: 38776.78 Da        Isoelectric Point: 5.0367

>NTDB_id=52160 LPV_RS04920 WP_014843599.1 1061209..1062273(+) (pilM) [Legionella pneumophila subsp. pneumophila]
MLKLLKPKHRSILGIDISSSAVKILEISGSGEDICVEGYGREEIPASALEGNMIKDVDVVANCIKKLVERLKFTSKNVAL
AVPDSAVISKVVQINEGLTDLEMEELVVIEADKYIPYPIDEINLDFEVLGHSAKSSSLLDVLIVASRAENVNTRVEAAHR
AGLEPKVVDVESYAVERSVQQIAQELPASGQDKIVAIVDIGANYTHLFVLHGMRLIFSREEKFGGMQLVEAIAEHYHMNL
EQAIALKNQGKLPEDYESAVLEPFKDMILLQIKRTLQFFYSTSQHGFVDHILLAGGMARQPGLASLIQEQLGVTTTVANP
LSHMSFGKKVNLDVINSDAPTLMVACGLALRHVE

Nucleotide


Download         Length: 1065 bp        

>NTDB_id=52160 LPV_RS04920 WP_014843599.1 1061209..1062273(+) (pilM) [Legionella pneumophila subsp. pneumophila]
GTGCTCAAATTGCTTAAACCTAAGCATCGTTCAATTCTTGGCATTGACATTAGTTCTTCCGCAGTGAAAATTCTGGAAAT
ATCAGGTTCCGGAGAGGACATTTGTGTTGAAGGATATGGTCGTGAAGAAATACCTGCCTCTGCCCTAGAAGGAAATATGA
TCAAGGATGTCGATGTAGTAGCGAATTGTATCAAAAAATTAGTAGAAAGATTGAAGTTTACATCTAAAAATGTGGCATTG
GCTGTACCTGATTCGGCTGTTATCAGTAAAGTAGTGCAAATTAATGAAGGGTTAACTGACCTTGAAATGGAAGAGCTTGT
CGTTATTGAGGCGGATAAGTACATTCCTTACCCAATAGATGAAATAAACCTGGATTTTGAAGTGTTAGGCCATTCAGCCA
AGAGCTCATCACTGCTTGATGTTTTAATCGTGGCATCAAGGGCAGAAAACGTTAATACCCGTGTTGAAGCAGCTCATAGA
GCAGGGCTGGAACCCAAAGTTGTTGACGTTGAATCTTATGCAGTAGAGCGTTCGGTACAACAAATTGCGCAAGAATTACC
AGCAAGTGGGCAAGACAAAATTGTTGCAATAGTAGATATTGGAGCCAATTATACTCACTTATTTGTTTTGCATGGTATGC
GACTAATCTTTTCAAGAGAAGAAAAATTTGGAGGTATGCAACTTGTTGAAGCTATTGCAGAACACTATCATATGAATTTG
GAGCAGGCTATTGCCCTAAAAAATCAGGGTAAACTACCGGAGGACTACGAATCTGCTGTATTAGAGCCTTTTAAGGACAT
GATTCTTTTGCAGATCAAACGTACTTTGCAGTTTTTTTATTCAACCAGCCAACATGGATTTGTAGACCATATTTTATTGG
CGGGAGGAATGGCAAGACAACCAGGATTGGCATCGCTTATTCAAGAACAGTTAGGAGTGACTACTACAGTGGCAAATCCA
CTATCCCATATGTCTTTTGGTAAAAAAGTGAATTTGGATGTGATTAACAGTGATGCGCCTACACTGATGGTGGCTTGTGG
GTTGGCTTTGAGGCATGTCGAGTAA

Domains

Predicted by InterproScan.

Type IV pilus assembly protein PilM; (PilM_2)

(14-352)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4T1VG56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilM Legionella pneumophila strain ERS1305867

99.718

100

0.997
  comM Acinetobacter nosocomialis M2

42.373

100

0.424
  pilM Acinetobacter baumannii D1279779

42.09

100

0.421
  comM Acinetobacter baylyi ADP1

40.678

100

0.407

Multiple sequence alignment