Detailed information NTG0521072

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: JMO16_RS08230
• Genome accession: NZ_CP080566
• Coordinates: 1671167..1671478 (-)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: A0A0H2XGS7
• Organism: Staphylococcus aureus strain HL20835 isolate HL20835
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1666167..1676478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO16_RS08195 (JMO16_08195)	gcvPA	1666669..1668015 (-)	1347	WP_000019691.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
JMO16_RS08200 (JMO16_08200)	gcvT	1668035..1669126 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
JMO16_RS08205 (JMO16_08205)	-	1669285..1669809 (-)	525	WP_001015120.1	shikimate kinase	-
JMO16_RS08210 (JMO16_08210)	-	1669799..1669945 (-)	147	WP_001792109.1	hypothetical protein	-
JMO16_RS08215 (JMO16_08215)	comGF	1670042..1670539 (-)	498	WP_001788897.1	competence type IV pilus minor pilin ComGF	Machinery gene
JMO16_RS08220 (JMO16_08220)	comGE	1670457..1670756 (-)	300	WP_000844410.1	hypothetical protein	Machinery gene
JMO16_RS08225 (JMO16_08225)	comGD	1670743..1671189 (-)	447	WP_001788899.1	competence type IV pilus minor pilin ComGD	Machinery gene
JMO16_RS08230 (JMO16_08230)	comGC	1671167..1671478 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
JMO16_RS08235 (JMO16_08235)	-	1671492..1671929 (-)	438	Protein_1629	type II secretion system F family protein	-
JMO16_RS08240 (JMO16_08240)	-	1672029..1673201 (+)	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
JMO16_RS08245 (JMO16_08245)	-	1673253..1673894 (-)	642	Protein_1631	type II secretion system F family protein	-
JMO16_RS08250 (JMO16_08250)	comGA	1673866..1674840 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
JMO16_RS08255 (JMO16_08255)	-	1674892..1675515 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
JMO16_RS08260 (JMO16_08260)	-	1675512..1675841 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=521072 JMO16_RS08230 WP_000472256.1 1671167..1671478(-) (comGC) [Staphylococcus aureus strain HL20835 isolate HL20835]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=521072 JMO16_RS08230 WP_000472256.1 1671167..1671478(-) (comGC) [Staphylococcus aureus strain HL20835 isolate HL20835]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

3D structure

• AlphaFold DB: A0A0H2XGS7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comGC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comGC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369