Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SMUGS5_RS08960 Genome accession   NC_018089
Coordinates   1849080..1850021 (-) Length   313 a.a.
NCBI ID   WP_002282214.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1844080..1855021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS08920 (SMUGS5_08900) - 1844090..1845289 (-) 1200 WP_002263443.1 acetate kinase -
  SMUGS5_RS08925 (SMUGS5_08905) comYH 1845348..1846301 (-) 954 WP_014835049.1 class I SAM-dependent methyltransferase Machinery gene
  SMUGS5_RS10590 comYG 1846356..1846727 (-) 372 WP_042899578.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUGS5_RS10595 comGF 1846728..1847156 (-) 429 Protein_1741 competence type IV pilus minor pilin ComGF -
  SMUGS5_RS08940 (SMUGS5_08915) comYE 1847143..1847436 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUGS5_RS08945 (SMUGS5_08920) comYD 1847408..1847812 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUGS5_RS08950 (SMUGS5_08925) comYC 1847799..1848113 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUGS5_RS08955 (SMUGS5_08930) comYB 1848113..1849144 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUGS5_RS08960 (SMUGS5_08935) comYA 1849080..1850021 (-) 942 WP_002282214.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUGS5_RS08965 (SMUGS5_08940) - 1850151..1850534 (-) 384 WP_002263434.1 DUF1033 family protein -
  SMUGS5_RS08970 (SMUGS5_08945) rpoC 1850662..1854291 (-) 3630 WP_002263433.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35752.18 Da        Isoelectric Point: 8.9362

>NTDB_id=52063 SMUGS5_RS08960 WP_002282214.1 1849080..1850021(-) (comYA) [Streptococcus mutans GS-5]
MVQKLGRKIIAKAVQNKAQDIYIIPKKESYELYMRIGNERRFIDVYDHHFMANLISHFKFVAGMNVGEKRRSQLGSCDYS
YDEGKVISLRLSSVGDYRGYESLVIRLLFSGRHDLKFWFNSMDLILNEIKGRGLYLFSGPVGSGKTSLMYQLVKLRFETK
QIITIEDPVEIKQDNMLQLQLNESIDMTYDNLIKLSLRHRPDILIIGEIRDKETARAVIRASLTGAMVFSTIHAKSIPGV
YARMLELGTSSEELQNALRGIVYQRLIGGGGIIDFAKGDYQNHSAKKWNKQIYDLFTAGYITEGEAQAEEIED

Nucleotide


Download         Length: 942 bp        

>NTDB_id=52063 SMUGS5_RS08960 WP_002282214.1 1849080..1850021(-) (comYA) [Streptococcus mutans GS-5]
ATGGTTCAAAAATTAGGTAGAAAAATCATTGCCAAAGCTGTTCAAAATAAAGCACAAGATATCTATATTATTCCTAAAAA
AGAATCTTATGAGCTTTATATGAGAATAGGGAATGAAAGGAGGTTCATTGATGTTTATGACCATCATTTCATGGCTAATC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAGAAAAGACGAAGTCAGCTGGGCTCTTGCGATTATTCT
TATGATGAAGGGAAAGTTATTTCATTAAGGTTATCAAGTGTAGGAGATTATCGTGGTTATGAAAGTTTGGTTATTCGCTT
ACTTTTTTCTGGACGTCACGATTTAAAATTCTGGTTTAACAGTATGGATTTGATTTTAAATGAAATCAAGGGGCGAGGGC
TTTATCTTTTTTCAGGTCCAGTTGGAAGTGGCAAAACAAGTTTGATGTATCAATTGGTAAAACTAAGATTTGAGACCAAA
CAGATAATTACCATTGAAGATCCTGTGGAAATTAAGCAAGATAATATGTTACAACTGCAGCTTAATGAAAGTATTGATAT
GACTTATGATAATTTAATTAAATTATCTCTGAGGCATCGTCCGGATATTTTAATTATTGGAGAAATTCGAGATAAAGAAA
CCGCCAGAGCTGTTATTAGAGCAAGTCTTACAGGGGCAATGGTATTCTCAACTATCCATGCTAAAAGCATTCCAGGTGTT
TATGCTAGGATGTTAGAATTGGGTACTAGTTCAGAAGAATTACAAAATGCTTTGCGTGGTATTGTTTATCAACGTTTAAT
AGGGGGAGGAGGGATTATTGACTTTGCCAAAGGGGATTATCAAAACCACTCAGCAAAAAAGTGGAACAAACAAATTTATG
ACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

99.361

100

0.994
  comYA Streptococcus mutans UA140

99.042

100

0.99
  comYA Streptococcus gordonii str. Challis substr. CH1

66.773

100

0.668
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.346

99.681

0.661
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

99.361

0.652
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521

Multiple sequence alignment