Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SMUGS5_RS08955 Genome accession   NC_018089
Coordinates   1848113..1849144 (-) Length   343 a.a.
NCBI ID   WP_255262721.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1843113..1854144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS08915 tnpA 1843414..1843877 (-) 464 Protein_1737 IS200/IS605 family transposase -
  SMUGS5_RS08920 (SMUGS5_08900) - 1844090..1845289 (-) 1200 WP_002263443.1 acetate kinase -
  SMUGS5_RS08925 (SMUGS5_08905) comYH 1845348..1846301 (-) 954 WP_014835049.1 class I SAM-dependent methyltransferase Machinery gene
  SMUGS5_RS10590 comYG 1846356..1846727 (-) 372 WP_042899578.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUGS5_RS10595 comGF 1846728..1847156 (-) 429 Protein_1741 competence type IV pilus minor pilin ComGF -
  SMUGS5_RS08940 (SMUGS5_08915) comYE 1847143..1847436 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUGS5_RS08945 (SMUGS5_08920) comYD 1847408..1847812 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUGS5_RS08950 (SMUGS5_08925) comYC 1847799..1848113 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUGS5_RS08955 (SMUGS5_08930) comYB 1848113..1849144 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUGS5_RS08960 (SMUGS5_08935) comYA 1849080..1850021 (-) 942 WP_002282214.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUGS5_RS08965 (SMUGS5_08940) - 1850151..1850534 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39844.46 Da        Isoelectric Point: 9.5151

>NTDB_id=52062 SMUGS5_RS08955 WP_255262721.1 1848113..1849144(-) (comYB) [Streptococcus mutans GS-5]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=52062 SMUGS5_RS08955 WP_255262721.1 1848113..1849144(-) (comYB) [Streptococcus mutans GS-5]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGTATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CACGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

100

100

1
  comYB Streptococcus mutans UA140

99.417

100

0.994
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment