Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   I6H72_RS07465 Genome accession   NZ_CP066055
Coordinates   1472239..1473180 (+) Length   313 a.a.
NCBI ID   WP_006268058.1    Uniprot ID   F9P809
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1467239..1478180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS07430 (I6H72_07430) - 1467371..1468567 (+) 1197 WP_006268026.1 phosphoglycerate kinase -
  I6H72_RS07435 (I6H72_07435) - 1468633..1468839 (+) 207 WP_006268044.1 hypothetical protein -
  I6H72_RS07440 (I6H72_07440) - 1468842..1469126 (+) 285 WP_006268247.1 2'-5' RNA ligase family protein -
  I6H72_RS07445 (I6H72_07445) - 1469265..1469795 (+) 531 WP_150225828.1 FUSC family protein -
  I6H72_RS07450 (I6H72_07450) - 1469872..1470231 (+) 360 WP_003073972.1 MerR family transcriptional regulator -
  I6H72_RS07455 (I6H72_07455) glnA 1470270..1471616 (+) 1347 WP_025272015.1 type I glutamate--ammonia ligase -
  I6H72_RS07460 (I6H72_07460) - 1471804..1472124 (+) 321 WP_198457773.1 DUF1033 family protein -
  I6H72_RS07465 (I6H72_07465) comYA 1472239..1473180 (+) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H72_RS07470 (I6H72_07470) comYB 1473122..1474144 (+) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H72_RS07475 (I6H72_07475) comYC 1474141..1474458 (+) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H72_RS07480 (I6H72_07480) comYD 1474418..1474846 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H72_RS07485 (I6H72_07485) comGE/cglE 1474818..1475111 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H72_RS07490 (I6H72_07490) comGF/cglF 1475095..1475532 (+) 438 WP_198457774.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H72_RS07495 (I6H72_07495) comGG 1475513..1475839 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  I6H72_RS07500 (I6H72_07500) comYH 1475924..1476877 (+) 954 WP_198457775.1 class I SAM-dependent methyltransferase Machinery gene
  I6H72_RS07505 (I6H72_07505) - 1476924..1478123 (+) 1200 WP_198457776.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35973.15 Da        Isoelectric Point: 6.3145

>NTDB_id=516870 I6H72_RS07465 WP_006268058.1 1472239..1473180(+) (comYA) [Streptococcus constellatus strain FDAARGOS_1015]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFANQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHITFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=516870 I6H72_RS07465 WP_006268058.1 1472239..1473180(+) (comYA) [Streptococcus constellatus strain FDAARGOS_1015]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTTAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGCGATTATCAA
TATAGTGACAAGAAAACGTCGCTACGGTTATCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCAATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P809

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

76.038

100

0.76
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.719

100

0.757
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.662

99.361

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

43.478

88.179

0.383