Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   I6H72_RS07470 Genome accession   NZ_CP066055
Coordinates   1473122..1474144 (+) Length   340 a.a.
NCBI ID   WP_037592679.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1468122..1479144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS07435 (I6H72_07435) - 1468633..1468839 (+) 207 WP_006268044.1 hypothetical protein -
  I6H72_RS07440 (I6H72_07440) - 1468842..1469126 (+) 285 WP_006268247.1 2'-5' RNA ligase family protein -
  I6H72_RS07445 (I6H72_07445) - 1469265..1469795 (+) 531 WP_150225828.1 FUSC family protein -
  I6H72_RS07450 (I6H72_07450) - 1469872..1470231 (+) 360 WP_003073972.1 MerR family transcriptional regulator -
  I6H72_RS07455 (I6H72_07455) glnA 1470270..1471616 (+) 1347 WP_025272015.1 type I glutamate--ammonia ligase -
  I6H72_RS07460 (I6H72_07460) - 1471804..1472124 (+) 321 WP_198457773.1 DUF1033 family protein -
  I6H72_RS07465 (I6H72_07465) comYA 1472239..1473180 (+) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H72_RS07470 (I6H72_07470) comYB 1473122..1474144 (+) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H72_RS07475 (I6H72_07475) comYC 1474141..1474458 (+) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H72_RS07480 (I6H72_07480) comYD 1474418..1474846 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H72_RS07485 (I6H72_07485) comGE/cglE 1474818..1475111 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H72_RS07490 (I6H72_07490) comGF/cglF 1475095..1475532 (+) 438 WP_198457774.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H72_RS07495 (I6H72_07495) comGG 1475513..1475839 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  I6H72_RS07500 (I6H72_07500) comYH 1475924..1476877 (+) 954 WP_198457775.1 class I SAM-dependent methyltransferase Machinery gene
  I6H72_RS07505 (I6H72_07505) - 1476924..1478123 (+) 1200 WP_198457776.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38877.00 Da        Isoelectric Point: 9.6572

>NTDB_id=516871 I6H72_RS07470 WP_037592679.1 1473122..1474144(+) (comYB) [Streptococcus constellatus strain FDAARGOS_1015]
MQQDISLLSRQKRKKLSIVRQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEKTYVEKMKEGLATGKPFSEIMASLGFSD
SVVTQLSLAELHGNLSLSLNKIEEYLENVSTVKKKLIEVATYPFILLIFLVFIMLGLRNYLLPQLERQNSATQLISQLPQ
IFLGSLGVVLVLLAIGFYWFRKSSKIVVFSFLARLPFGGTFIQAYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWEKFFSRINQAMNLVQPLVFVFVALV
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=516871 I6H72_RS07470 WP_037592679.1 1473122..1474144(+) (comYB) [Streptococcus constellatus strain FDAARGOS_1015]
ATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAGGCAGAAAAAAGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGCGGCTTTCATTTAGCAGAAATGATTGATTTTTTGAAGCGGAGTGCCCTGCTAGAAAAAA
CCTATGTGGAAAAGATGAAAGAGGGTTTAGCAACAGGAAAACCTTTTTCAGAAATTATGGCTAGTTTAGGATTTTCAGAT
AGTGTTGTCACCCAGCTTTCACTGGCAGAGCTACATGGGAATCTCTCACTCAGCCTGAATAAGATTGAGGAATACTTGGA
AAATGTCTCAACAGTCAAGAAAAAGTTAATTGAGGTAGCCACTTATCCATTCATTTTACTTATTTTTTTAGTATTCATTA
TGTTAGGGCTGCGCAATTATTTACTTCCGCAGTTAGAACGCCAAAACAGTGCAACGCAGCTGATTAGTCAGTTGCCGCAA
ATTTTTCTGGGTTCATTAGGAGTAGTCCTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCAAAAATAGT
AGTGTTTAGCTTCTTGGCTCGACTTCCTTTTGGTGGAACTTTTATTCAAGCGTATTTGACAGCTTATTATGCGCGCGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGACTTAGAAGTTGCGCTGCAAAATGGTCAGGAATTTTCCCAAGTGGTTAAACACTACCCGTTTTTTAA
AAAGGAATTGGGTTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGGTGTGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGAAGTTTTTTAGTCGGATCAATCAAGCTATGAACTTAGTACAGCCGCTTGTCTTTGTTTTTGTGGCACTGGTT
ATTGTTTTATTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.235

100

0.732
  comGB/cglB Streptococcus mitis NCTC 12261

70.03

99.118

0.694
  comGB/cglB Streptococcus mitis SK321

68.657

98.529

0.676
  comGB/cglB Streptococcus pneumoniae TIGR4

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae R6

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae Rx1

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae D39

68.358

98.529

0.674
  comYB Streptococcus mutans UA159

62.281

100

0.626
  comYB Streptococcus mutans UA140

61.988

100

0.624
  comGB Lactococcus lactis subsp. cremoris KW2

52.226

99.118

0.518