Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   I6H72_RS07485 Genome accession   NZ_CP066055
Coordinates   1474818..1475111 (+) Length   97 a.a.
NCBI ID   WP_003035318.1    Uniprot ID   I0SGQ0
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1469818..1480111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS07450 (I6H72_07450) - 1469872..1470231 (+) 360 WP_003073972.1 MerR family transcriptional regulator -
  I6H72_RS07455 (I6H72_07455) glnA 1470270..1471616 (+) 1347 WP_025272015.1 type I glutamate--ammonia ligase -
  I6H72_RS07460 (I6H72_07460) - 1471804..1472124 (+) 321 WP_198457773.1 DUF1033 family protein -
  I6H72_RS07465 (I6H72_07465) comYA 1472239..1473180 (+) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H72_RS07470 (I6H72_07470) comYB 1473122..1474144 (+) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H72_RS07475 (I6H72_07475) comYC 1474141..1474458 (+) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H72_RS07480 (I6H72_07480) comYD 1474418..1474846 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H72_RS07485 (I6H72_07485) comGE/cglE 1474818..1475111 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H72_RS07490 (I6H72_07490) comGF/cglF 1475095..1475532 (+) 438 WP_198457774.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H72_RS07495 (I6H72_07495) comGG 1475513..1475839 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  I6H72_RS07500 (I6H72_07500) comYH 1475924..1476877 (+) 954 WP_198457775.1 class I SAM-dependent methyltransferase Machinery gene
  I6H72_RS07505 (I6H72_07505) - 1476924..1478123 (+) 1200 WP_198457776.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10936.85 Da        Isoelectric Point: 10.4707

>NTDB_id=516874 I6H72_RS07485 WP_003035318.1 1474818..1475111(+) (comGE/cglE) [Streptococcus constellatus strain FDAARGOS_1015]
MENLRKQYVRGTILLEALLASAVFAFIVTLLLGQIHQSRQTENDLLKKEEVLRVANMALQTKQSHLTINGIEVRVKKSQQ
GIQIYHGKELIVGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=516874 I6H72_RS07485 WP_003035318.1 1474818..1475111(+) (comGE/cglE) [Streptococcus constellatus strain FDAARGOS_1015]
ATGGAAAATTTAAGAAAACAATACGTTAGAGGAACGATTTTATTAGAAGCTTTATTGGCATCGGCTGTTTTTGCGTTTAT
TGTGACCTTGTTATTGGGGCAGATCCATCAGTCTCGACAGACAGAAAATGATTTACTGAAAAAAGAAGAAGTTCTAAGAG
TGGCTAATATGGCATTACAAACAAAGCAAAGCCATTTAACAATAAACGGTATTGAAGTTCGTGTTAAAAAAAGTCAACAA
GGCATCCAGATTTATCATGGGAAGGAGCTGATTGTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SGQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

42.424

100

0.433
  comYE Streptococcus mutans UA159

42.424

100

0.433