Detailed information NTG0511046

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: STCNRZ385_RS08980
• Genome accession: NZ_CP065495
• Coordinates: 1729026..1729352 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain CNRZ385
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1724026..1734352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ385_RS08935	-	1724292..1724630 (-)	339	WP_228024408.1	CPBP family intramembrane glutamic endopeptidase	-
STCNRZ385_RS08940	-	1724674..1724949 (-)	276	WP_084830830.1	CAAX protease	-
STCNRZ385_RS08945 (STCNRZ385_08925)	-	1724961..1725158 (-)	198	WP_084826167.1	helix-turn-helix transcriptional regulator	-
STCNRZ385_RS08950 (STCNRZ385_08930)	-	1725407..1726600 (-)	1194	WP_084826168.1	acetate kinase	-
STCNRZ385_RS08955 (STCNRZ385_08935)	comYH	1726656..1727612 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STCNRZ385_RS08960 (STCNRZ385_08940)	comGG	1727657..1727974 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STCNRZ385_RS08965 (STCNRZ385_08945)	comYF	1727952..1728389 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
STCNRZ385_RS08970 (STCNRZ385_08950)	comGE	1728373..1728666 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STCNRZ385_RS08975 (STCNRZ385_08955)	comYD	1728638..1729066 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STCNRZ385_RS08980 (STCNRZ385_08960)	comYC	1729026..1729352 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STCNRZ385_RS08985 (STCNRZ385_08965)	comYB	1729349..1730449 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
STCNRZ385_RS08990 (STCNRZ385_08970)	comGA/cglA/cilD	1730331..1731272 (-)	942	WP_180483385.1	competence type IV pilus ATPase ComGA	Machinery gene
STCNRZ385_RS08995 (STCNRZ385_08975)	-	1731353..1731715 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=511046 STCNRZ385_RS08980 WP_002946126.1 1729026..1729352(-) (comYC) [Streptococcus thermophilus strain CNRZ385]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=511046 STCNRZ385_RS08980 WP_002946126.1 1729026..1729352(-) (comYC) [Streptococcus thermophilus strain CNRZ385]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAAAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361