Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   STAVA1121_RS08925 Genome accession   NZ_CP065488
Coordinates   1693600..1694541 (-) Length   313 a.a.
NCBI ID   WP_022096896.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA1121     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1688600..1699541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS08885 (STAVA1121_08765) - 1688677..1689870 (-) 1194 WP_347131256.1 acetate kinase -
  STAVA1121_RS08890 (STAVA1121_08770) comYH 1689926..1690882 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STAVA1121_RS08895 (STAVA1121_08775) comGG 1690927..1691244 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  STAVA1121_RS08900 (STAVA1121_08780) comYF 1691222..1691659 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  STAVA1121_RS08905 (STAVA1121_08785) comGE 1691643..1691936 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  STAVA1121_RS08910 (STAVA1121_08790) comYD 1691908..1692336 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  STAVA1121_RS08915 (STAVA1121_08795) comYC 1692296..1692622 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STAVA1121_RS08920 (STAVA1121_08800) comGB 1692619..1693718 (-) 1100 Protein_1699 competence type IV pilus assembly protein ComGB -
  STAVA1121_RS08925 (STAVA1121_08805) comGA/cglA/cilD 1693600..1694541 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  STAVA1121_RS08930 (STAVA1121_08810) - 1694622..1694984 (-) 363 WP_011226630.1 DUF1033 family protein -
  STAVA1121_RS08935 (STAVA1121_08815) rpoC 1695143..1698781 (-) 3639 WP_087010199.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35409.56 Da        Isoelectric Point: 6.3927

>NTDB_id=510691 STAVA1121_RS08925 WP_022096896.1 1693600..1694541(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain AVA1121]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=510691 STAVA1121_RS08925 WP_022096896.1 1693600..1694541(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain AVA1121]
ATGGTAACAGAATTTGCTAAGGAAATGATAAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTTTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCTGAACGTCGGGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

63.259

100

0.633
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.538

99.681

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377