Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   STT19_RS08845 Genome accession   NZ_CP065487
Coordinates   1710338..1711279 (-) Length   313 a.a.
NCBI ID   WP_014622005.1    Uniprot ID   A0A2X3UX10
Organism   Streptococcus thermophilus strain ST19     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1705338..1716279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT19_RS08805 (STT19_08830) - 1705414..1706607 (-) 1194 WP_084825660.1 acetate kinase -
  STT19_RS08810 (STT19_08835) comYH 1706663..1707619 (-) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  STT19_RS08815 (STT19_08840) comGG 1707664..1707981 (-) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG -
  STT19_RS08820 (STT19_08845) comYF 1707959..1708396 (-) 438 WP_084825661.1 competence type IV pilus minor pilin ComGF Machinery gene
  STT19_RS08825 (STT19_08850) comGE 1708380..1708673 (-) 294 WP_023909978.1 competence type IV pilus minor pilin ComGE -
  STT19_RS08830 (STT19_08855) comYD 1708645..1709073 (-) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  STT19_RS08835 (STT19_08860) comYC 1709033..1709359 (-) 327 WP_023909980.1 competence type IV pilus major pilin ComGC Machinery gene
  STT19_RS08840 (STT19_08865) comYB 1709356..1710456 (-) 1101 WP_159340986.1 competence type IV pilus assembly protein ComGB Machinery gene
  STT19_RS08845 (STT19_08870) comYA 1710338..1711279 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  STT19_RS08850 (STT19_08875) - 1711360..1711722 (-) 363 WP_023909982.1 DUF1033 family protein -
  STT19_RS08855 (STT19_08880) rpoC 1711880..1715518 (-) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35421.62 Da        Isoelectric Point: 6.3927

>NTDB_id=510632 STT19_RS08845 WP_014622005.1 1710338..1711279(-) (comYA) [Streptococcus thermophilus strain ST19]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=510632 STT19_RS08845 WP_014622005.1 1710338..1711279(-) (comYA) [Streptococcus thermophilus strain ST19]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAAGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3UX10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377