Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I2437_RS08975 Genome accession   NZ_CP065061
Coordinates   1910274..1911212 (-) Length   312 a.a.
NCBI ID   WP_165628048.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ33     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1905274..1916212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2437_RS08935 (IEMOCGPF_01784) - 1905298..1906497 (-) 1200 WP_012678817.1 acetate kinase -
  I2437_RS08940 (IEMOCGPF_01785) comYH 1906557..1907510 (-) 954 WP_043024962.1 class I SAM-dependent methyltransferase Machinery gene
  I2437_RS08945 (IEMOCGPF_01786) comGG 1907572..1907934 (-) 363 WP_012677238.1 competence type IV pilus minor pilin ComGG -
  I2437_RS08950 (IEMOCGPF_01787) comYF 1907912..1908346 (-) 435 WP_043983927.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2437_RS08955 (IEMOCGPF_01788) comGE 1908333..1908623 (-) 291 WP_014622143.1 competence type IV pilus minor pilin ComGE -
  I2437_RS08960 (IEMOCGPF_01789) comGD 1908580..1909005 (-) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  I2437_RS08965 (IEMOCGPF_01790) comGC/cglC 1908983..1909306 (-) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  I2437_RS08970 (IEMOCGPF_01791) comYB 1909307..1910341 (-) 1035 WP_228274584.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2437_RS08975 (IEMOCGPF_01792) comGA/cglA 1910274..1911212 (-) 939 WP_165628048.1 competence type IV pilus ATPase ComGA Machinery gene
  I2437_RS08980 (IEMOCGPF_01793) - 1911369..1912037 (-) 669 WP_165628047.1 ATP-binding cassette domain-containing protein -
  I2437_RS08985 (IEMOCGPF_01794) - 1912039..1914042 (-) 2004 WP_111689762.1 DUF1430 domain-containing protein -
  I2437_RS09780 - 1914107..1914307 (-) 201 WP_206157838.1 lactococcin 972 family bacteriocin -
  I2437_RS08995 (IEMOCGPF_01795) - 1914567..1914932 (-) 366 WP_165628045.1 DUF1033 family protein -
  I2437_RS09000 (IEMOCGPF_01796) - 1914993..1916039 (-) 1047 WP_206157839.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35212.42 Da        Isoelectric Point: 6.8988

>NTDB_id=506630 I2437_RS08975 WP_165628048.1 1910274..1911212(-) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MVQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGAKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQQIDQLLAEGHLNTKQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=506630 I2437_RS08975 WP_165628048.1 1910274..1911212(-) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGCTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTTACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATCAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGTGTTTAC
GCTAGGCTGTTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAAGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.387

99.359

0.679
  comYA Streptococcus mutans UA140

63.344

99.679

0.631
  comYA Streptococcus mutans UA159

63.344

99.679

0.631
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.29

99.359

0.609
  comGA Lactococcus lactis subsp. cremoris KW2

53.055

99.679

0.529
  comGA Latilactobacillus sakei subsp. sakei 23K

39.661

94.551

0.375