Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I2433_RS00680 Genome accession   NZ_CP065056
Coordinates   114542..115480 (+) Length   312 a.a.
NCBI ID   WP_206152300.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 109542..120480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2433_RS00660 (JDBNIEOD_00128) - 109706..110752 (+) 1047 WP_206151850.1 acyltransferase family protein -
  I2433_RS00665 (JDBNIEOD_00129) - 110813..111178 (+) 366 WP_037580641.1 DUF1033 family protein -
  I2433_RS00670 (JDBNIEOD_00130) - 111714..113717 (+) 2004 WP_206152298.1 DUF1430 domain-containing protein -
  I2433_RS00675 (JDBNIEOD_00131) - 113719..114387 (+) 669 WP_206152299.1 ATP-binding cassette domain-containing protein -
  I2433_RS00680 (JDBNIEOD_00132) comGA/cglA 114542..115480 (+) 939 WP_206152300.1 competence type IV pilus ATPase ComGA Machinery gene
  I2433_RS00685 (JDBNIEOD_00133) comYB 115413..116447 (+) 1035 WP_231151265.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2433_RS00690 (JDBNIEOD_00134) comGC/cglC 116448..116771 (+) 324 WP_012677235.1 competence type IV pilus major pilin ComGC Machinery gene
  I2433_RS00695 (JDBNIEOD_00135) comGD 116749..117174 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  I2433_RS00700 (JDBNIEOD_00136) comGE 117131..117421 (+) 291 WP_014622143.1 competence type IV pilus minor pilin ComGE -
  I2433_RS00705 (JDBNIEOD_00137) comYF 117408..117842 (+) 435 WP_206152549.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2433_RS00710 (JDBNIEOD_00138) comGG 117820..118182 (+) 363 WP_206152302.1 competence type IV pilus minor pilin ComGG -
  I2433_RS00715 (JDBNIEOD_00139) comYH 118244..119197 (+) 954 WP_037580627.1 class I SAM-dependent methyltransferase Machinery gene
  I2433_RS00720 (JDBNIEOD_00140) - 119257..120456 (+) 1200 WP_012678817.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35331.65 Da        Isoelectric Point: 7.3645

>NTDB_id=506339 I2433_RS00680 WP_206152300.1 114542..115480(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGVKVSLRLSAVGDYQGQESLVIRLLYHCRRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=506339 I2433_RS00680 WP_206152300.1 114542..115480(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGCGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGTTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATTGTCGACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCAGTCGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTCTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCACAAAAGGAATTTGAACATCATCAAGCCAACCGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.065

99.359

0.676
  comYA Streptococcus mutans UA159

63.023

99.679

0.628
  comYA Streptococcus mutans UA140

63.023

99.679

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.29

99.359

0.609
  comYA Streptococcus gordonii str. Challis substr. CH1

60.968

99.359

0.606
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.679

0.526
  comGA Latilactobacillus sakei subsp. sakei 23K

40.909

91.667

0.375