Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   STH8232_RS09230 Genome accession   NC_017581
Coordinates   1776206..1777147 (-) Length   313 a.a.
NCBI ID   WP_014622005.1    Uniprot ID   A0A2X3UX10
Organism   Streptococcus thermophilus JIM 8232     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1771206..1782147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS09190 (STH8232_2140) - 1771282..1772475 (-) 1194 WP_014622001.1 acetate kinase -
  STH8232_RS09195 (STH8232_2141) comYH 1772531..1773487 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STH8232_RS09200 (STH8232_2142) comGG 1773532..1773849 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  STH8232_RS09205 (STH8232_2143) comYF 1773827..1774264 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  STH8232_RS09210 (STH8232_2144) comGE 1774248..1774541 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  STH8232_RS09215 (STH8232_2145) comYD 1774513..1774941 (-) 429 WP_257608452.1 competence type IV pilus minor pilin ComGD Machinery gene
  STH8232_RS09220 (STH8232_2146) comYC 1774901..1775227 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STH8232_RS09225 (STH8232_2147) comYB 1775224..1776324 (-) 1101 WP_014622004.1 competence type IV pilus assembly protein ComGB Machinery gene
  STH8232_RS09230 (STH8232_2148) comYA 1776206..1777147 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  STH8232_RS09235 (STH8232_2149) - 1777228..1777590 (-) 363 WP_014622006.1 DUF1033 family protein -
  STH8232_RS09240 (STH8232_2150) rpoC 1777749..1781387 (-) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35421.62 Da        Isoelectric Point: 6.3927

>NTDB_id=49022 STH8232_RS09230 WP_014622005.1 1776206..1777147(-) (comYA) [Streptococcus thermophilus JIM 8232]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=49022 STH8232_RS09230 WP_014622005.1 1776206..1777147(-) (comYA) [Streptococcus thermophilus JIM 8232]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3UX10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377

Multiple sequence alignment