Detailed information NTG0049018

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STH8232_RS09205
• Genome accession: NC_017581
• Coordinates: 1773827..1774264 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus JIM 8232
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1768827..1779264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STH8232_RS09165 (STH8232_2135)	-	1768891..1769553 (-)	663	WP_011681679.1	CPBP family intramembrane glutamic endopeptidase	-
STH8232_RS09170 (STH8232_2136)	-	1769650..1770093 (-)	444	WP_011681680.1	hypothetical protein	-
STH8232_RS12040 (STH8232_2137)	-	1770167..1770505 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
STH8232_RS12045 (STH8232_2138)	-	1770549..1770824 (-)	276	WP_011681681.1	hypothetical protein	-
STH8232_RS09185 (STH8232_2139)	-	1770836..1771033 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STH8232_RS09190 (STH8232_2140)	-	1771282..1772475 (-)	1194	WP_014622001.1	acetate kinase	-
STH8232_RS09195 (STH8232_2141)	comYH	1772531..1773487 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STH8232_RS09200 (STH8232_2142)	comGG	1773532..1773849 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STH8232_RS09205 (STH8232_2143)	comYF	1773827..1774264 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STH8232_RS09210 (STH8232_2144)	comGE	1774248..1774541 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STH8232_RS09215 (STH8232_2145)	comYD	1774513..1774941 (-)	429	WP_257608452.1	competence type IV pilus minor pilin ComGD	Machinery gene
STH8232_RS09220 (STH8232_2146)	comYC	1774901..1775227 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STH8232_RS09225 (STH8232_2147)	comYB	1775224..1776324 (-)	1101	WP_014622004.1	competence type IV pilus assembly protein ComGB	Machinery gene
STH8232_RS09230 (STH8232_2148)	comYA	1776206..1777147 (-)	942	WP_014622005.1	competence type IV pilus ATPase ComGA	Machinery gene
STH8232_RS09235 (STH8232_2149)	-	1777228..1777590 (-)	363	WP_014622006.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=49018 STH8232_RS09205 WP_014608742.1 1773827..1774264(-) (comYF) [Streptococcus thermophilus JIM 8232]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=49018 STH8232_RS09205 WP_014608742.1 1773827..1774264(-) (comYF) [Streptococcus thermophilus JIM 8232]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441