Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   STH8232_RS09225 Genome accession   NC_017581
Coordinates   1775224..1776324 (-) Length   366 a.a.
NCBI ID   WP_014622004.1    Uniprot ID   -
Organism   Streptococcus thermophilus JIM 8232     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1770224..1781324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS12045 (STH8232_2138) - 1770549..1770824 (-) 276 WP_011681681.1 hypothetical protein -
  STH8232_RS09185 (STH8232_2139) - 1770836..1771033 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  STH8232_RS09190 (STH8232_2140) - 1771282..1772475 (-) 1194 WP_014622001.1 acetate kinase -
  STH8232_RS09195 (STH8232_2141) comYH 1772531..1773487 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STH8232_RS09200 (STH8232_2142) comGG 1773532..1773849 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  STH8232_RS09205 (STH8232_2143) comYF 1773827..1774264 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  STH8232_RS09210 (STH8232_2144) comGE 1774248..1774541 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  STH8232_RS09215 (STH8232_2145) comYD 1774513..1774941 (-) 429 WP_257608452.1 competence type IV pilus minor pilin ComGD Machinery gene
  STH8232_RS09220 (STH8232_2146) comYC 1774901..1775227 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STH8232_RS09225 (STH8232_2147) comYB 1775224..1776324 (-) 1101 WP_014622004.1 competence type IV pilus assembly protein ComGB Machinery gene
  STH8232_RS09230 (STH8232_2148) comYA 1776206..1777147 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  STH8232_RS09235 (STH8232_2149) - 1777228..1777590 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41801.86 Da        Isoelectric Point: 10.1084

>NTDB_id=49021 STH8232_RS09225 WP_014622004.1 1775224..1776324(-) (comYB) [Streptococcus thermophilus JIM 8232]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVTQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRDLGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=49021 STH8232_RS09225 WP_014622004.1 1775224..1776324(-) (comYB) [Streptococcus thermophilus JIM 8232]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTACCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGATCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(52-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.094

93.443

0.505
  comYB Streptococcus mutans UA159

54.094

93.443

0.505
  comYB Streptococcus gordonii str. Challis substr. CH1

50.585

93.443

0.473
  comGB/cglB Streptococcus mitis NCTC 12261

49.849

90.437

0.451
  comGB/cglB Streptococcus mitis SK321

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae Rx1

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae D39

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae R6

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae TIGR4

49.085

89.617

0.44
  comGB Lactococcus lactis subsp. cremoris KW2

45.152

90.164

0.407

Multiple sequence alignment