Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NMBM01240355_RS00665 Genome accession   NC_017517
Coordinates   126426..127613 (+) Length   395 a.a.
NCBI ID   WP_014581710.1    Uniprot ID   -
Organism   Neisseria meningitidis M01-240355     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 121426..132613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM01240355_RS00650 (NMBM01240355_0110) - 122346..122945 (+) 600 WP_002216221.1 DUF4390 domain-containing protein -
  NMBM01240355_RS00655 (NMBM01240355_0111) - 122945..125065 (+) 2121 WP_014581708.1 PAS domain-containing sensor histidine kinase -
  NMBM01240355_RS00660 (NMBM01240355_0112) - 125058..126335 (+) 1278 WP_014581709.1 sigma-54 dependent transcriptional regulator -
  NMBM01240355_RS00665 (NMBM01240355_0113) dprA 126426..127613 (+) 1188 WP_014581710.1 DNA-processing protein DprA Machinery gene
  NMBM01240355_RS00670 (NMBM01240355_0114) - 127639..128100 (+) 462 WP_002215351.1 DUF494 family protein -
  NMBM01240355_RS00675 (NMBM01240355_0115) topA 128172..130478 (+) 2307 WP_002256289.1 type I DNA topoisomerase -
  NMBM01240355_RS00680 (NMBM01240355_0116) - 130551..131246 (-) 696 WP_002216227.1 hypothetical protein -
  NMBM01240355_RS00685 (NMBM01240355_0117) - 131266..131817 (-) 552 WP_002256290.1 hypothetical protein -
  NMBM01240355_RS00690 (NMBM01240355_0118) - 131936..132313 (+) 378 WP_002233408.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 395 a.a.        Molecular weight: 41829.82 Da        Isoelectric Point: 5.9333

>NTDB_id=48087 NMBM01240355_RS00665 WP_014581710.1 126426..127613(+) (dprA) [Neisseria meningitidis M01-240355]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGSRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide


Download         Length: 1188 bp        

>NTDB_id=48087 NMBM01240355_RS00665 WP_014581710.1 126426..127613(+) (dprA) [Neisseria meningitidis M01-240355]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCCCTGTCGCAAGTAACGCTGGTGGTTGAAGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCAGTCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(341-388)

DNA recombination-mediator protein A (DNA_processg_A)

(79-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Neisseria gonorrhoeae MS11

96.709

100

0.967
  dprA Neisseria gonorrhoeae strain FA1090

96.456

100

0.965
  dprA Neisseria meningitidis strain C311

90.176

100

0.906
  dprA Neisseria meningitidis MC58

90.176

100

0.906
  dprA Glaesserella parasuis strain SC1401

40.314

96.709

0.39
  dprA Vibrio cholerae strain A1552

37.28

100

0.375

Multiple sequence alignment